Skip to main content
Nucleic Acids Research logoLink to Nucleic Acids Research
. 1977 Mar;4(3):573–583. doi: 10.1093/nar/4.3.573

Circular dichroism study of polyriboxanthylic acid.

M Spodheim-Maurizot, M Leng
PMCID: PMC342463  PMID: 17098

Abstract

We report in the present paper the circular dichroism spectra of poly(X) at different pH and temperature values. The spectra are characteristic of three stable forms of poly(x) in the pH range of protonation of xanthosine. An electrostatic barrier is proposed to account for the hysteresis and metastability observed in a certain pH range. Some results on oligo(X) at basic pH are also presented. Poly(X) at basic pH is investigated also by hydrodynamic techniques.

Full text

PDF
573

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bachner L., Massoulié J. Dissociation thermique en plusieurs étapes de l'acide polyxanthylique. C R Acad Sci Hebd Seances Acad Sci D. 1971 Jun 7;272(23):2965–2968. [PubMed] [Google Scholar]
  2. Bachner L., Massoulié J. Etude de l'acide polyxanthylique et de ses complexes. Eur J Biochem. 1973 May;35(1):95–105. doi: 10.1111/j.1432-1033.1973.tb02814.x. [DOI] [PubMed] [Google Scholar]
  3. Brahms J., Maurizot J. C., Michelson A. M. Conformation and thermodynamic properties of oligocytidylic acids. J Mol Biol. 1967 May 14;25(3):465–480. doi: 10.1016/0022-2836(67)90199-4. [DOI] [PubMed] [Google Scholar]
  4. Brahms J., Michelson A. M., Van Holde K. E. Adenylate oligomers in single- and double-strand conformation. J Mol Biol. 1966 Feb;15(2):467–488. doi: 10.1016/s0022-2836(66)80122-5. [DOI] [PubMed] [Google Scholar]
  5. Christensen J. J., Rytting J. H., Izatt R. M. Thermodynamic pK, delta H-o, delta S-o, and delta Cp-o values for proton dissociation from several purines and their nucleosides in aqueous solution. Biochemistry. 1970 Dec 8;9(25):4907–4913. doi: 10.1021/bi00827a012. [DOI] [PubMed] [Google Scholar]
  6. Fikus M., Shugar D. Properties of poly-xanthylic acid and its reactions with potentially complementary homopolynucleotides. Acta Biochim Pol. 1969;16(1):55–82. [PubMed] [Google Scholar]
  7. Leng M., Michelson A. M. Polynucléotides. XI. Etude de la stabilité conformationelle de polynucléotides en fonction de la température. Biochim Biophys Acta. 1968 Jan 29;155(1):91–97. [PubMed] [Google Scholar]
  8. Michelson A. M., Monny C. Polynucleotide analogues. IX. Polyxanthylic acid. Biochim Biophys Acta. 1966 Dec 21;129(3):460–474. [PubMed] [Google Scholar]
  9. Pörschke D., Eigen M. Co-operative non-enzymic base recognition. 3. Kinetics of the helix-coil transition of the oligoribouridylic--oligoriboadenylic acid system and of oligoriboadenylic acid alone at acidic pH. J Mol Biol. 1971 Dec 14;62(2):361–381. doi: 10.1016/0022-2836(71)90433-5. [DOI] [PubMed] [Google Scholar]
  10. Spodheim M., Neumann E. Ionic strength dependence of the hysteresis in the polyriboadenylate-polyribouridylate system. Biophys Chem. 1975 Apr;3(2):109–124. doi: 10.1016/0301-4622(75)80001-9. [DOI] [PubMed] [Google Scholar]
  11. Thrierr J. C., Dourlent M., Leng M. A study of polyuridylic acid. J Mol Biol. 1971 Jun 28;58(3):815–830. doi: 10.1016/0022-2836(71)90042-8. [DOI] [PubMed] [Google Scholar]

Articles from Nucleic Acids Research are provided here courtesy of Oxford University Press

RESOURCES