Skip to main content
NCBI home page
Nucleic Acids Research logoLink to Nucleic Acids Research
. 1977 Aug;4(8):2549–2559.

Comparison of the nucleotide sequence of the messenger RNA for the major structural protein of SV40 with the DNA sequence encoding the amino acids of the protein

M L Celma 1, R Dhar 1, J Pan 1, S M Weissman 1
PMCID: PMC342591  PMID: 198746

Abstract

The 16S late mRNA from SV40 directs the synthesis of the major viral structural protein, VPl. We have compared the oligonucleotides in the 16S mRNA with those that would be present in a transcript of the portion of SV40 DNA coding for VPl. The results indicate that a segment of about 200 nucleotides of RNA transcribed from a distant part of SV40 DNA have become linked to the transcript of VPl codons by a bond resistant to phenol extraction and denaturation in formamide.

Full text

PDF
2549

Images in this article

2551Image
on p.2551
2552Image
on p.2552
2554Image
on p.2554
2556Image
on p.2556

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Aloni Y., Shani M., Reuveni Y. RNAs of simian virus 40 in productively infected monkey cells: kinetics of formation and decay in enucleate cells. Proc Natl Acad Sci U S A. 1975 Jul;72(7):2587–2591. doi: 10.1073/pnas.72.7.2587. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Dhar R., Subramanian K. N., Pan J., Weissman S. M. Structure of a large segment of the genome of simian virus 40 that does not encode known proteins. Proc Natl Acad Sci U S A. 1977 Mar;74(3):827–831. doi: 10.1073/pnas.74.3.827. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Dhar R., Subramanian K., Zain B. S., Pan J., Weissman S. M. Nucleotide sequence about the 3' terminus of SV40 DNA transcripts and the region where DNA synthesis is initiated. Cold Spring Harb Symp Quant Biol. 1975;39(Pt 1):153–160. doi: 10.1101/sqb.1974.039.01.021. [DOI] [PubMed] [Google Scholar]
  4. Dhar R., Zain S., Weissman S. M., Pan J., Subramanian K. Nucleotide sequences of RNA transcribed in infected cells and by Escherichia coli RNA polymerase from a segment of simian virus 40 DNA. Proc Natl Acad Sci U S A. 1974 Feb;71(2):371–375. doi: 10.1073/pnas.71.2.371. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Volckaert G., Contreras R., Soeda E., Van de Voorde A., Fiers W. Nucleotide sequence of simian virus 40 Hind H restriction fragment. J Mol Biol. 1977 Mar 5;110(3):467–510. doi: 10.1016/s0022-2836(77)80109-5. [DOI] [PubMed] [Google Scholar]

Articles from Nucleic Acids Research are provided here courtesy of Oxford University Press

RESOURCES