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. 1978 Nov;5(11):4065–4075. doi: 10.1093/nar/5.11.4065

A new RNA-RNA crosslinking reagent and its application to ribosomal 5S RNA.

R Wagner, R A Garrett
PMCID: PMC342734  PMID: 724507

Abstract

The synthesis of a new RNA specific bifunctional crosslinking reagent, 1.4-phenyl-diglyoxal, is described which reacts exclusively with guanosines. The properties of the crosslinked products enabled us to develop a straightforward method for identifying the reacted nucleotides. Results obtained with ribosomal 5S RNA of Escherichia coli demonstrate the formation of an intramolecular crosslink between guanosine-2 and guanosine-112 in the stem region.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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