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. 1975 Jan;2(1):131–141. doi: 10.1093/nar/2.1.131

Studies on the structure of replicative intermediates in bacteriophage M13 single stranded DNA synthesis.

B E Kessler-Liebscher, W L Staudenbauer, P H Hofschneider
PMCID: PMC342817  PMID: 1129143

Abstract

Pulse-labeled replicative intermediates in M 13 single stranded DNA synthesis can be separated by dye-buoyant density centrifugation into two major fractions: Supercoiled molecules (RI I) containing viral strands of more than one genome length, and "relaxed" molecules (RI II) with labeled DNA chains shorter than unit length. It is postulated that RI II molecules might be formed in vivo by site-specific nicking of RF I molecules.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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