Abstract
The role of thymine dimerization for previously reported U.V. induced conformational changes has been proved using acetophenone as sensitizer for the specific thymine dimerization upon irradiation at 313 nm. CD results demonstrate that formation of pyrimidine dimers cause typical conformational changes of the DNA B helix as observed on irradiation at 254 nm. Thus the primary role of adenine photoproducts may be excluded.
Full text
PDF




Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Lamola A. A. Specific formation of thymine dimers in DNA. Photochem Photobiol. 1969 Mar;9(3):291–294. doi: 10.1111/j.1751-1097.1969.tb07292.x. [DOI] [PubMed] [Google Scholar]
- Lang H., Luck G. Ultraviolet-light-induced conformational changes in DNA. Photochem Photobiol. 1973 Jun;17(6):387–393. doi: 10.1111/j.1751-1097.1973.tb06372.x. [DOI] [PubMed] [Google Scholar]
