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. 1976 Jan;3(1):69–78. doi: 10.1093/nar/3.1.69

DNA replication in eukaryotes: a model for the specific involvement of chromatin subunits.

D R Hewish
PMCID: PMC342878  PMID: 765971

Abstract

A model is proposed whereby eukaryotic DNA replication is specifically directed by the 200 base pair repeat structure of the DNA-histone complex. The model proposes a mechanism for the sequential, bidirectional replication of DNA from initial origin points on the chromatin fibre and is consistent with the known properties of eukaryotic DNA replication. Several predictions can be made from the model which are amenable to testing.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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