Table 1.
SNP | Chromosome | Allele | HapMap CEU | HapMap ASW | Δ (CEU-ASW) | HapMap YRI | African American control20,21 | Duke African American CLL | CRC African American CLL | Duke/CRC African American CLL | P* | P† |
---|---|---|---|---|---|---|---|---|---|---|---|---|
rs798443 | 2 | A | 0.82 | 0.14 | 0.68 | 0.035 | 0.18 | 0.15 | 0.18 | 0.17 | .75 | .72 |
rs1462309 | 3 | T | 0.84 | 0.22 | 0.62 | 0.028 | 0.15 | 0.21 | 0.15 | 0.17 | .67 | .32 |
rs10041728 | 5 | G | 0.93 | 0.23 | 0.71 | 0.031 | 0.21 | 0.29 | 0.25 | 0.26 | .10 | .66 |
rs4896780 | 6 | A | 0.17 | 0.86 | 0.69 | 0.99 | 0.85 | 0.85 | 0.79 | 0.81 | .25 | .42 |
rs4885162 | 13 | C | 0.75 | 0.12 | 0.63 | 0.014 | 0.14 | 0.14 | 0.13 | 0.14 | 1 | .99 |
rs2246695 | 14 | T | 0.82 | 0.16 | 0.67 | 0.003 | 0.16 | 0.21 | 0.18 | 0.20 | .17 | .71 |
rs12594483 | 15 | A | 0.071 | 0.88 | 0.81 | 1 | 0.82 | 0.85 | 0.75 | 0.79 | .19 | .12 |
rs7187359 | 16 | A | 0.21 | 0.84 | 0.62 | 0.99 | 0.84 | 0.80 | 0.85 | 0.83 | .81 | .49 |
Comparison of allele frequencies of Duke/CRC African American CLL with MD Anderson controls.
Comparison of allele frequencies of Duke African American CLL with CRC African American CLL.