Abstract
Oligonucleotides and nucleoside phosphoramidates can be synthesized in high yields by a combined use of triphenyl phosphite and 2,2′-dipyridyl diselenide as a coupling reagent.
Full text
PDF















Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BANDURSKI R. S., AXELROD B. The chromatographic identification of some biologically important phosphate esters. J Biol Chem. 1951 Nov;193(1):405–410. [PubMed] [Google Scholar]
- Büchi H., Khorana H. G. CV. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Chemical synthesis of an icosadeoxyribonucleotide corresponding to the nucleotide sequence 31 to 50. J Mol Biol. 1972 Dec 28;72(2):251–288. doi: 10.1016/0022-2836(72)90148-9. [DOI] [PubMed] [Google Scholar]
- HANES C. S., ISHERWOOD F. A. Separation of the phosphoric esters on the filter paper chromatogram. Nature. 1949 Dec 31;164(4183):1107-12, illust. doi: 10.1038/1641107a0. [DOI] [PubMed] [Google Scholar]
- JACOB T. M., KHORANA H. G. STUDIES ON POLYNUCLEOTIDES. XXXVII. THE SYNTHESIS OF SPECIFIC DEOXYRIBOPOLYNUCLEOTIDES. FURTHER EXAMINATION OF THE APPROACH INVOLVING STEPWISE SYNTHESIS. J Am Chem Soc. 1965 Jan 20;87:368–374. doi: 10.1021/ja01080a038. [DOI] [PubMed] [Google Scholar]
- Lohrmann R., Söll D., Hayatsu H., Ohtsuka E., Khorana H. G. Studies on polynucleotides. LI. Syntheses of the 64 possible ribotrinucleotides derived from the four major ribomononucleotides. J Am Chem Soc. 1966 Feb 20;88(4):819–829. doi: 10.1021/ja00956a039. [DOI] [PubMed] [Google Scholar]
- Moon M. W., Khorana H. G. Studies on polynucleotides. LV. The use of mesitoyl chloride in the synthesis of internucleotide bonds. J Am Chem Soc. 1966 Apr 20;88(8):1805–1809. doi: 10.1021/ja00960a039. [DOI] [PubMed] [Google Scholar]
- Mukaiyama T., Hashimoto M. Synthesis of oligothymidylates and nucleoside cyclic phosphates by oxidation-reduction condensation. J Am Chem Soc. 1972 Nov 29;94(24):8528–8532. doi: 10.1021/ja00779a039. [DOI] [PubMed] [Google Scholar]
- Ohtsuka E., Murao K., Ubasawa M., Ikehara M. A new method for the synthesis of protected ribooligonucleotides with 3'-phosphate end groups. J Am Chem Soc. 1969 Mar 12;91(6):1537–1538. doi: 10.1021/ja01034a047. [DOI] [PubMed] [Google Scholar]
