Skip to main content
NCBI home page
Nucleic Acids Research logoLink to Nucleic Acids Research
. 1976 Jun;3(6):1549–1559. doi: 10.1093/nar/3.6.1549

Protonated polynucleotide structures, 20. Interaction between poly(dG)-poly(dC) and poly(rC).1.

B L Haas, M T Sarocchi, W Guschilbauer
PMCID: PMC343012  PMID: 8771

Abstract

A study of the interaction between poly(dG)-poly(dC) and poly(rC) demonstrates that, at neutral pH and high ionic strength, there is replacement of the dC strand by poly(rC). At acid pH, formation of a triple-stranded complex which equally may involve the replacement phenomenon is observed. There is no evidence for interaction at neutral pH between poly(dG)-poly(dC) and oligo(rC), while a three-stranded complex is formed at acid pH. These data are consistent with the studies of comparative stabilities of double stranded deoxy or ribo polymers and deoxy-ribo hybrids.

Full text

PDF
1549

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Chamberlin M. J. Comparative properties of DNA, RNA, and hybrid homopolymer pairs. Fed Proc. 1965 Nov-Dec;24(6):1446–1457. [PubMed] [Google Scholar]
  2. Darlix J. L. Stimultaneous purification of Escherichia coli termination factor rho, RNAase III and RNAase H. Eur J Biochem. 1975 Feb 21;51(2):369–376. doi: 10.1111/j.1432-1033.1975.tb03937.x. [DOI] [PubMed] [Google Scholar]
  3. Guschlbauer W. Protonated polynucleotide structures. 16. Thermodynamics of the melting of the acid form of polycytidylic acid. Nucleic Acids Res. 1975 Mar;2(3):353–360. doi: 10.1093/nar/2.3.353. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Haas B. L., Guschlbauer W. Protonated polynucleotide structures. 18. Interaction of oligocytidylates with poly (G). Nucleic Acids Res. 1976 Jan;3(1):205–218. doi: 10.1093/nar/3.1.205. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. INMAN R. B. TRANSITIONS OF DNA HOMOPOLYMERS. J Mol Biol. 1964 Sep;9:624–637. doi: 10.1016/s0022-2836(64)80171-6. [DOI] [PubMed] [Google Scholar]
  6. Morgan A. R., Wells R. D. Specificity of the three-stranded complex formation between double-stranded DNA and single-stranded RNA containing repeating nucleotide sequences. J Mol Biol. 1968 Oct 14;37(1):63–80. doi: 10.1016/0022-2836(68)90073-9. [DOI] [PubMed] [Google Scholar]
  7. Murray N. L., Morgan A. R. Enzymatic and physical studies on the triplex dTn.dAn.rUn. Can J Biochem. 1973 Apr;51(4):436–449. doi: 10.1139/o73-051. [DOI] [PubMed] [Google Scholar]
  8. Thiele D., Guschlbauer W. Protonated polynucleotide structures. IX. Disproportionation of poly (G)-poly (C) in acid medium. Biopolymers. 1971;10(1):143–157. doi: 10.1002/bip.360100111. [DOI] [PubMed] [Google Scholar]

Articles from Nucleic Acids Research are provided here courtesy of Oxford University Press

RESOURCES