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. 1976 Jul;3(7):1647–1658. doi: 10.1093/nar/3.7.1647

"Fingerprinting" high molecular weight RNA by two-dimensional gel electrophoresis: application to poliovirus RNA.

Y F Lee, E Wimmer
PMCID: PMC343025  PMID: 184435

Abstract

Conditions are described under which complete RNase T1 digests of high molecular weight RNA can be separated into numerous components by two-dimensional gel electrophoresis. Small and large oligonucleotides (n = 1 - 2c0) can be resolved without losses. The procedure yields fingerprints which are diagnostic for a particular species of RNA and an index of its purity as will be shown for the genomes of poliovirus type 1 and 2.

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Selected References

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