Skip to main content
Nucleic Acids Research logoLink to Nucleic Acids Research
. 1975 Sep;2(9):1493–1502. doi: 10.1093/nar/2.9.1493

The sequence dependence of circular dichroism spectra of DNA duplexes.

S Arnott, S Arnott
PMCID: PMC343517  PMID: 809757

Abstract

The three satellite DNAs of Drosophila virilis, that approximate to poly d(CAAACTA)-poly d(TAGTTTG), poly d(TAAACTA)-poly d(TAGTTTA), poly d(CAAATTA)-poly d(TAATTTG), the satellite DNA of Drosophila melanogaster that approximates to poly d(AATAT)-poly d(ATATT), the synthetic DNA duplexes, poly dG-poly dC, poly d(AT)-poly d(AT), poly d(AAT)-poly d(ATT), poly d(AAC)-poly d(GTT), poly d(TAC)-poly d(GTA) and the block copolymer d(C15A15)-d(T15G15) all have circular dichroism spectra consistent with the propositions that they have the same molecular geometry in solution and that it is the kind and frequency of nucleotide triplet sequences that determines their spectral characteristics. Poly dA-poly dT is apparently an exception.

Full text

PDF

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Arnott S., Chandrasekaran R., Hukins D. W., Smith P. J., Watts L. Structural details of double-helix observed for DNAs containing alternating purine and pyrimidine sequences. J Mol Biol. 1974 Sep 15;88(2):523–533. doi: 10.1016/0022-2836(74)90499-9. [DOI] [PubMed] [Google Scholar]
  2. Arnott S., Selsing E. Structures for the polynucleotide complexes poly(dA) with poly (dT) and poly(dT) with poly(dA) with poly (dT). J Mol Biol. 1974 Sep 15;88(2):509–521. doi: 10.1016/0022-2836(74)90498-7. [DOI] [PubMed] [Google Scholar]
  3. Burd J. F., Wells R. D. Synthesis and characterization of the duplex block polymer d(C15A15)-d(T15G15). J Biol Chem. 1974 Nov 25;249(22):7094–7801. [PubMed] [Google Scholar]
  4. Gall J. G., Atherton D. D. Satellite DNA sequences in Drosophila virilis. J Mol Biol. 1974 Jan 5;85(4):633–664. doi: 10.1016/0022-2836(74)90321-0. [DOI] [PubMed] [Google Scholar]
  5. Gratzer W. B., Hill L. R., Owen R. J. Circular dichroism of DNA. Eur J Biochem. 1970 Aug;15(2):209–214. doi: 10.1111/j.1432-1033.1970.tb00996.x. [DOI] [PubMed] [Google Scholar]
  6. Gray D. M. A circular dichroism study of poly dG, poly dC, and poly dG:dC. Biopolymers. 1974;13(10):2087–2102. doi: 10.1002/bip.1974.360131011. [DOI] [PubMed] [Google Scholar]
  7. Gray D. M., Gall J. G. The circular dichroism of a Drosophila melanogaster satellite DNA. J Mol Biol. 1974 Jan 5;85(4):677–679. [PubMed] [Google Scholar]
  8. Gray D. M., Ratliff R. L., Williams D. L. The circular dichroism of poly d(AAT):d(ATT) and poly r(AAU):r(AUU). A test of the first-neighbor hypothesis. Biopolymers. 1973 Jun;12(6):1233–1245. doi: 10.1002/bip.1973.360120604. [DOI] [PubMed] [Google Scholar]
  9. Wells R. D., Larson J. E., Grant R. C., Shortle B. E., Cantor C. R. Physicochemical studies on polydeoxyribonucleotides containing defined repeating nucleotide sequences. J Mol Biol. 1970 Dec 28;54(3):465–497. doi: 10.1016/0022-2836(70)90121-x. [DOI] [PubMed] [Google Scholar]

Articles from Nucleic Acids Research are provided here courtesy of Oxford University Press

RESOURCES