Abstract
A dinucleoside monophosphate, 6,2′-anhydro-6-oxy-1-β-D-arabinofuranosyluracil-phosphoryl- (3′-5′)-6,2′-anhydro-6-oxy-1-β-D-arabinofuranosyluracil (I) was synthesized by the condensation reaction using DCC from 5′-monomethoxytrityl derivative(VII) and 3′-acetyl-5′-phosphate(X) of the monomer units. Yield was ca. 70%. UV of compound I showed no hypochromicity and its CD spectrum showed only a trough at 252 nm. No temperature dependency of ε and [Q] values was observed. These results suggested an unstacked random conformation for I.
Complex formation of I with cycloadenosine oligomer could not be detected under the experimental condition.
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