Table 1. Effects of Intracerebral Injection on Acoustic Startle Reactivity.
Wild-type | DAT KO | |
---|---|---|
Prefrontal cortex | ||
Vehicle | 221.4±37.5 | 139.4±25.4 |
Nisoxetine 2 μg/side | ND | 156.2±29.1 |
Nisoxetine 8 μg/side | 195.3±36.9 | 164.1±29.5 |
Nucleus accumbens | ||
Vehicle | 161.6±30.9 | 131.9±31.3 |
Nisoxetine 8 μg/side | 130.7±21.8 | 144.6±27.5 |
Abbreviations: DAT KO, dopamine transporter knockout mice; ND, not determined.
Each value represents the mean startle magnitude±SEM.