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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Psychoneuroendocrinology. 2012 May 29;38(1):84–93. doi: 10.1016/j.psyneuen.2012.05.001

Figure 3.

Figure 3

Baseline sex differences in gene expression of Gr, Bag1, Fkbp5, Ppid, and Src1 following chronic adolescent stress. Samples were collected immediately upon removal from the colony room four days after the final chronic stress exposure. RT-PCR of transcripts in the hippocampus was conducted. Female control expression values were normalized to male control expression values to determine inherent sex differences in gene expression (A). Female adolescent rats express less Ppid in the hippocampus than male adolescent rats (dotted line) (A). Gene expression values were normalized to same sex controls for subsequent comparisons. (B) Baseline Gr and (D) Fkbp5 were unaltered due to adolescent stress in either sex. (C) Baseline Bag1 and (E) Ppid were increased due to adolescent stress in female, but not male, adolescent rats. Chronic adolescent stress increased Src1 expression compared to controls, but no difference was found between individual groups. * p < 0.05 t test (A). * p < 0.05 Bonferroni post hoc test (C, E). N = 7–8. Data are presented as mean ± SEM.