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. 1975 Aug;2(8):1321–1328. doi: 10.1093/nar/2.8.1321

Rat hepatoma cells nucleolar DNA. II. A possible model of nucleolar DNA organisation.

F Amalric, J P Zalta
PMCID: PMC344384  PMID: 170594

Abstract

A model of nucleolar DNA organization has been established. Three clearly defined main components are found in ascites hepatoma cell nucleolar DNA by CsCl gradient analysis. A linear arrangement for nucleolar DNA and a model of DNA organization in the neighbourhood of a set of ribosomal genes, which may play a fundamental role in the elaboration of nucleolar chromatin tertiary structure, are presented.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Amalric F., Bernard S., Simard R. Detection of single-stranded DNA in the nucleolus. Nat New Biol. 1973 May 9;243(123):38–41. [PubMed] [Google Scholar]
  2. Bram S., Ris H. On the structure of nucleohistone. J Mol Biol. 1971 Feb 14;55(3):325–336. doi: 10.1016/0022-2836(71)90321-4. [DOI] [PubMed] [Google Scholar]
  3. Bram S. The function of the structure of DNA in chromosomes. Biochimie. 1972;54(8):1005–1011. doi: 10.1016/s0300-9084(72)80051-8. [DOI] [PubMed] [Google Scholar]
  4. Britten R. J., Davidson E. H. Gene regulation for higher cells: a theory. Science. 1969 Jul 25;165(3891):349–357. doi: 10.1126/science.165.3891.349. [DOI] [PubMed] [Google Scholar]
  5. Crick F. General model for the chromosomes of higher organisms. Nature. 1971 Nov 5;234(5323):25–27. doi: 10.1038/234025a0. [DOI] [PubMed] [Google Scholar]
  6. Georgiev G. P., Ryskov A. P., Coutelle C., Mantieva V. L., Avakyan E. R. On the structure of transcriptional unit in mammalian cells. Biochim Biophys Acta. 1972 Jan 31;259(2):259–283. doi: 10.1016/0005-2787(72)90066-4. [DOI] [PubMed] [Google Scholar]
  7. Hamkalo B. A., Miller O. L., Jr Electronmicroscopy of genetic activity. Annu Rev Biochem. 1973;42:379–396. doi: 10.1146/annurev.bi.42.070173.002115. [DOI] [PubMed] [Google Scholar]
  8. Kourilsky P., Manteuil S., Zamansky M. H., Gros F. DNA-RNA hybridization at low temperature in the presence of urea. Biochem Biophys Res Commun. 1970 Nov 25;41(4):1080–1087. doi: 10.1016/0006-291x(70)90196-8. [DOI] [PubMed] [Google Scholar]
  9. Ohta T., Kimura M. Functional organization of genetic material as a product of molecular evolution. Nature. 1971 Sep 10;233(5315):118–119. doi: 10.1038/233118a0. [DOI] [PubMed] [Google Scholar]
  10. Pardon J. F., Wilkins M. H., Richards B. M. Super-helical model for nucleohistone. Nature. 1967 Jul 29;215(5100):508–509. doi: 10.1038/215508a0. [DOI] [PubMed] [Google Scholar]
  11. Pardon J. F., Wilkins M. H., Richards B. M. Super-helical model for nucleohistone. Nature. 1967 Jul 29;215(5100):508–509. doi: 10.1038/215508a0. [DOI] [PubMed] [Google Scholar]
  12. Paul J. General theory of chromosome structure and gene activation in eukaryotes. Nature. 1972 Aug 25;238(5365):444–446. doi: 10.1038/238444a0. [DOI] [PubMed] [Google Scholar]
  13. Sutton W. D. Chromatin packing, repeated DNA sequences and gene control. Nat New Biol. 1972 May 17;237(72):70–71. doi: 10.1038/newbio237070a0. [DOI] [PubMed] [Google Scholar]

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