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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Neuropharmacology. 2012 Jul 20;64(1):53–64. doi: 10.1016/j.neuropharm.2012.07.020

Fig. 5.

Fig. 5

Normalized average evoked LFPs in LC following paw stimulation before and after different doses of ATM. During the first time-period (a and d; 30–90 min), although having no effect on single-unit activity in the LC, the lower dose (0.1 mg/kg) tended to flatten the LFP response to paw stimulation and significantly decreased both the Neg1 and Pos3 components. Higher doses increased negative components only. In the second time window considered (b and e; 90–150 min), 1 mg/kg of ATM significantly decreased the early negative and the positive components, whereas 0.1 mg/kg decreased only the Pos3. c) Example of the average LFP response before normalization and relative components. (* = p < .05, compared to pre-drug condition).