Table 3.

Estimation of probabilities (p) of the number of subjects responding at given levels relative to PBS→PBS-treated rats during TEST given groups size and a normal distribution by chi-squared test.

	PBS → PBS (n = 8)			MOR → PBS (n = 19)			MOR → NLX (n= 10)
Subjects during TEST in PBS → PBS group	Expected number of subjects	Number of subjects observed	p	Expected number of subjects	Number of subjects observed	p	Expected number of subjects	Number of subjects observed	p
> 0 SDs	4	4	0.317	9.5	9	0.819	5	4	0.527
> 1 SDs	1.269	1	0.365	3.014	6	0.061	1.587	1	0.612
> 2 SDs	0.182	0	0.374	0.432	4	4×10-8	0.228	0	0.629
> 3 SDs	0.0108	0	0.472	0.026	3	4×10-77	0.014	0	0.907
> 4 SDs	3×10-4	0	0.479	0.001	2	10-99<	3×10-4	0	0.986
> 5 SDs	2×10-6	0	0.479	5×10-6	`	10-99<	3×10-6	0	0.999
> 6 SDs	8×10-9	0	0.480	2×10-8	1	10-99<	1×10-8	0	1.000

See Results for complete explanation of analysis method. p values (chi-squared test) less than 0.05 are bolded.