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. 2012 Aug 16;4(8):1289–1304. doi: 10.3390/v4081289

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© 2012 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Alignment of the amino acid residues corresponding to those defining the VP4 neutralization domains (designated as 8-1, 8-2, 8-3 and 8-4 in the VP8* subunit (A) and 5-1, 5-2, 5-3, 5-4 and 5-5 in the VP5* subunit (B) of VP4) [24]) between the P[8] strains in Rotarix™ and RotaTeq™ and Chinese RVA strains Y128, R588 and E1911. Green indicates the residues that differ from those of both Rotarix™ and RotaTeq™. Red indicates the residues identical to those of RotaTeq™, but different from those of Rotarix™. Blue indicates the residues identical to those of Rotarix™, but different from those of RotaTeq™.