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. 1984 Feb;81(4):1189–1192. doi: 10.1073/pnas.81.4.1189

X chromosome-linked muscular dystrophy (mdx) in the mouse.

G Bulfield, W G Siller, P A Wight, K J Moore
PMCID: PMC344791  PMID: 6583703

Abstract

An X chromosome-linked mouse mutant (gene symbol, mdx) has been found that has elevated plasma levels of muscle creatine kinase and pyruvate kinase and exhibits histological lesions characteristic of muscular dystrophy. The mutants show mild clinical symptoms and are viable and fertile. Linkage analysis with four X chromosome loci indicates that mdx maps in the Hq Bpa region of the mouse X chromosome. This gives a gene order of mdx-Tfm-Pgk-1-Ags, the same as for the equivalent genes on the human X chromosome.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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