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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1984 Feb;81(3):785–787. doi: 10.1073/pnas.81.3.785

Direct observation of delta-crystallin accumulation by laser light-scattering spectroscopy in the chicken embryo lens.

S T Sun, T Tanaka, I Nishio, J Peetermans, J V Maizel Jr, J Piatigorsky
PMCID: PMC344921  PMID: 6583678

Abstract

By using the technique of laser light-scattering spectroscopy, direct observation has been made on the intracellular accumulation of a crystallin protein within the cells of chicken embryo lens during the process of development. Appearance of delta-crystallin has been detected as early as day 4, and its concentration reaches a plateau at day 19. The measurements constitute a noninvasive determination of accumulation of protein molecules that specifically characterize the process of cell differentiation.

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Selected References

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