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. 1984 Feb;81(3):788–792. doi: 10.1073/pnas.81.3.788

Lysosomes are associated with microtubules and not with intermediate filaments in cultured fibroblasts.

M Collot, D Louvard, S J Singer
PMCID: PMC344922  PMID: 6366790

Abstract

Double immunofluorescent labeling experiments for lysosomes and either microtubules or vimentin intermediate filaments in cultured well-spread fibroblasts show a remarkable degree of superposition of the lysosomes and the microtubules. Under two different sets of conditions where the microtubules and intermediate filaments are well segregated from one another, the lysosomes remain codistributed with the microtubules. It is suggested that this specific association of lysosomes with microtubules reflects some type(s) of linkage(s) between them and that such linkages may play an important role in the location and intracellular transport of lysosomes inside cells.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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