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Indian Journal of Microbiology logoLink to Indian Journal of Microbiology
. 2010 Mar 16;50(3):345–348. doi: 10.1007/s12088-010-0027-8

Re-emergence of glanders in India — Report of Maharashtra state

Praveen Malik 1,, S K Khurana 1, S K Dwivedi 1
PMCID: PMC3450061  PMID: 23100851

Abstract

Glanders, a notifiable highly contagious disease primarily of equids, is a disease of high zoonotic importance. Caused by gram-negative bacillus, Burkholderia mallei, the disease was restricted to certain pockets of India with sporadic cases. Recently, a major outbreak of glanders occurred in India starting from Maharashtra. Following clinical signs and symptoms and laboratory investigations on serum, nasal swab and pus swab samples, it was confirmed as glanders among equines in Pune and Panchgani areas of Maharashtra. One pus sample and three nasal swabs yielded B. mallei isolates while 23 serum samples were found positive for glanders by complement fixation test (CFT). The disease was successfully controlled in the state by following strategies for prevention of spread of the disease to other areas in accordance with Glanders and Farcy Act, 1899. Follow up of the occurrence in Maharashtra revealed negative status based on testing and physical surveillance on more than 3,500 equines thereafter. Investigations indicated that the nidus of infection may be present elsewhere in North India.

Keywords: Glanders, Burkholderia mallei, Equines, Horse, Complement fixation test

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