Abstract
Objective
To determine the efficacy of intravenous dexamethasone in reducing postrhinoplasty edema.
Design
A prospective, randomized clinical trial with placebo control.
Setting
Department of Otorhinolaryngology, Al-Sabah and Zain Hospital, Kuwait.
Subject
Eighty-four patients (male = 28; female = 56) aged between 20 and 40 years, undergoing open rhinoplasty with hump removal and bilateral lateral osteotomies were enrolled in this study.
Intervention
Patients were randomized to receive two doses of 10 mg of dexamethasone intravenously or placebo, first dose during surgery and second dose 12 hours after surgery.
Main outcome measures
Patients were evaluated postoperatively at 24 hours, days 2, 5, 7 and 10 for periorbital edema.
Results
10 mg of dexamethasone given intravenously during rhinoplasty and a second dose 12 hours after surgery, reduced postoperative periorbital edema significantly.
Conclusion
This study showed a statistically significant benefit of dexamethasone over placebo in reducing periorbital edema after rhinoplasty. No complications were attributed to the administration of dexamethasone.
Keywords: Rhinoplasty, Dexamethasone, Lateral osteotomy, Edema
Full Text
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Contributor Information
Monther Ali Alajmi, Email: monther67@hotmail.com.
Gopalan Kavitha, Email: kavient_raj@yahoo.com.
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