Abstract
This study was done with an aim to assess the reliability and diagnostic accuracy of fine needle aspiration biopsy of intraosseous jaw lesions. Of the 42 cases, adequate material for cytologic evaluation was obtained in 35 cases. Malignant cells were found in 9 of 35 cases. FNAB diagnosis was confirmed by histopathology in all 9 of these specimens (100% accuracy). The FNAB diagnosis of benign lesions was confirmed in 19 of 26 cases (73% accuracy). The most common benign lesions were odontogenic cysts, followed by fibro-osseous and giant cell lesions. Incorrect diagnosis was related to lack of architectural context of the FNAB material, inadequate quantity of the aspirate and sampling of a non-representative part of a large lesion. Thus FNAB is a useful, simple, fairly reliable and outpatient procedure for diagnosis of intra-osseous jaw lesions, especially to distinguish between malignant and benign jaw lesions.
Keywords: FNAB, Intra-osseous, Benign, Malignant, Jaw lesions
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References
- 1.Platt J.C., Davidson D., Nelson C.L., et al. Fine needle aspiration biopsy. An analysis of 89 head and neck cases. J Oral Maxillofac Surg. 1990;48:706. doi: 10.1016/0278-2391(90)90053-5. [DOI] [PubMed] [Google Scholar]
- 2.Daskalopoulou D., Rapidis A.D., Maounis N., et al. Fine needle aspiration cytology in tumors and tumor like conditions of the oral and maxillofacial region. Diagnostic reliability and limitations. Cancer. 1997;81:238. doi: 10.1002/(sici)1097-0142(19970825)81:4<238::aid-cncr6>3.0.co;2-l. [DOI] [PubMed] [Google Scholar]
- 3.Ramzy I., Aufdemorte T.B., Duncan D.L. Diagnosis of radiolucent lesions of the jaws by fine needle aspiration biopsy. Acta Cytol. 1985;29:419–424. [PubMed] [Google Scholar]
- 4.Vetrani A., Fulciniti F., Boschi B.D., et al. Fine needle aspiration biopsy diagnosis of giant cell tumor of bone: An experience with nine cases. Acta Cytol. 1990;34:863–867. [PubMed] [Google Scholar]
- 5.Akerman M., Dreinhofer K., Rydholm A., et al. Cytogenetic studies on fine needle aspiration samples from osteosarcoma and Ewing’s sarcoma. Diagn Cytopathol. 1996;15:17. doi: 10.1002/(SICI)1097-0339(199607)15:1<17::AID-DC5>3.0.CO;2-N. [DOI] [PubMed] [Google Scholar]
- 6.August M., Faquin W.C., Ferraro N.F., Kaban L.B. Fine needle aspiration biopsy of intra-osseous jaw lesions. J Oral Maxillofac Surg. 1999;57(II):1282–1287. doi: 10.1016/S0278-2391(99)90859-5. [DOI] [PubMed] [Google Scholar]
- 7.Günhann O., Onder T., Finci R. Fine needle aspiration cytology of oral cavity and jaw bone lesions. A report of 102 cases. Acta Cytol. 1993;37:135–141. [PubMed] [Google Scholar]
- 8.Günhan O. Fine needle aspiration cytology of ameloblastoma. A report of 10 cases. Acta Cytol. 1996;40(5):967–969. doi: 10.1159/000334010. [DOI] [PubMed] [Google Scholar]
- 9.Radhika S., Nijhawan R., Das A., Dey P. Ameloblastoma of the mandible: Diagnosis by fine needle aspiration cytology. Diagn Cytopathol. 1993;9:310–313. doi: 10.1002/dc.2840090313. [DOI] [PubMed] [Google Scholar]
- 10.Vege D.S., Borges A.M., Aggrawal K., Balasubramaniam G., Parikh D.M., Bhaser B. Oseosarcoma of the craniofacial bones. A clinico-pathological study. J Cranio Maxillofac Surg. 1991;19(2):90–93. doi: 10.1016/S1010-5182(05)80614-6. [DOI] [PubMed] [Google Scholar]
- 11.White V.A., Fanning C.V., Ayala A.G., Raymond A.K., Carrasco C.H., Murray J.A. Osteosarcoma and role of fine needle aspiration: A study of 51 cases. Cancer. 1998;62(6):1238–1246. doi: 10.1002/1097-0142(19880915)62:6<1238::AID-CNCR2820620632>3.0.CO;2-L. [DOI] [PubMed] [Google Scholar]
- 12.Clarke J.L., Unni K.K., Dahlin D.C., Devine K.D. Osteosarcoma of the jaw. Cancer. 1983;51:2311–2316. doi: 10.1002/1097-0142(19830615)51:12<2311::AID-CNCR2820511224>3.0.CO;2-Z. [DOI] [PubMed] [Google Scholar]