Skip to main content
Indian Journal of Otolaryngology and Head & Neck Surgery logoLink to Indian Journal of Otolaryngology and Head & Neck Surgery
. 2001 Jan;53(1):76–80. doi: 10.1007/BF02910990

The role of two enzymes (LDH and PHI) and a tumour marker (CEA) in the prognostic evalution of head and neck malignancy

A P S Narang 1, R S Greval 1, H Chopra 1, C S Kalra 1
PMCID: PMC3450875  PMID: 23119762

Abstract

A study of 30 patients with biopsy proven carcinoma of head and neck were taken and serum levels of CEA, LDH and PHI was estimated before treatment and 3 months post treatment. 30 patients were taken as controls for comparison. Pre- and past-treatment levels were statistically compared and the role of surgery, radiotherapy and chemotherapy compared. Variation with metastasis and with smoking was also evaluated.

Full Text

The Full Text of this article is available as a PDF (1.6 MB).

References

  • 1.Bhatia P.L., Singh M.M., chakravorty M. Enzymatic study in diagnosis of head and neck cancer. Ind. J. Otolaryngology. 1979;31:76–79. [Google Scholar]
  • 2.Khan N., Hameed S., Husain Z. Serum Cholinesterase and LDH levels in maglignaney of larynx and nasal cavity. Indian J. Otolaryngology. 1984;36:48–50. [Google Scholar]
  • 3.Lai H., Wig U., Nangla R. Serum CEA levels in Head and Neck Cancer. Indian J. Clin. Biochem. 1992;7:64–69. [Google Scholar]
  • 4.Mali K.L., Vyas C.R., et al. Serum LDH in different types of malignancy. J. Indian Assoc. 1985;83:371–72. [PubMed] [Google Scholar]
  • 5.Meeker W.R., Kashmiri R., Hunter L., Clapp W., et al. Clinical evaluation to CEA test. Arch. Surg. 1973;107:266–274. doi: 10.1001/archsurg.1973.01350200128027. [DOI] [PubMed] [Google Scholar]
  • 6.Schwartz M.A., West M. Serum enzymes in disease VIII. Glycolytic and oxidative enzymes and transaminases in patients with gastrointestinal carcinoma. Cancer. 1962;15:346–453. doi: 10.1002/1097-0142(196203/04)15:2<346::AID-CNCR2820150218>3.0.CO;2-W. [DOI] [PubMed] [Google Scholar]
  • 7.Vaid P., Shastri K. D., and Sharma D. C.: A clinico-biochemical study of PHI, Aliesterase and sulfhydry 1 group in 25 normal and 35 cancer suspects. Indian J. Cancer 448–453, 1974. [PubMed]
  • 8.Yadav S.P.S., Singh R., Goyal H.C., Kohli G.S., et al. LDH activity in head and neck cancer. Indian J. Otol & Head and Neck Surgery. 1994;3(1):21–24. [Google Scholar]

Articles from Indian Journal of Otolaryngology and Head & Neck Surgery are provided here courtesy of Springer

RESOURCES