Abstract
The present study is on 52 patient of acquired SNHL who were treated with Ginkgo biloba extract (Ginkocer) or conventional treatment (Neurobion, Arlidine & Vit -A) or both. The age range was 11–75 years with male: female - 3.1. Commonest probable etiology was presbyacusis (36.5%) followed by idiopathic (28.8%). Subjective improvement in hearing was comparable in both the ttreatment groups. Objective improvement (> 10 dB ) was seen with Ginkocer therapy only in cases of idiopathic (3). ototoxicity (1) head injury (1). It was maximum in <25 yrs. age and ranged between 11–50 dB. However, statistically it was not significant for age, sex, socioeconomic status, oral habits, Hb level, serum cholesterol and albumin: globulin ratio. Patients showing no effect of drug were almost comparable in both the groups. In conventional group the remaining patients demonstrated drug efficacy of 30% while in the Ginkocer group it was upto 60%. The mean improvement in tinnitus was 52.32% with Ginkocer and 50.09% with conventional treatment. Relative improvement with Ginkocer was found better by 15.56%, 21.94% & 9.09% in presbyacusis, idiopathic: and ototoxicity group as compared to conventional group.
Full Text
The Full Text of this article is available as a PDF (934.0 KB).
References
- 1.Chessebeout L., Herard J., Trevin J. Edude Comparativede drux varooregutaleus dans les hypo acouseies et les syndroms vertigo neus. Med. Nord. EST. 1979;3:534–539. [Google Scholar]
- 2.Coles Trial of an extract of Ginkgo Biloba for tinnitus & hearing loss Clinical Otolaryngology. 1988;13:501–502. [PubMed] [Google Scholar]
- 3.Dubreil C., Comparative therapeutic trial of Ginkgo biloba extract & Nicergoline in acute cochlear deafness. Presse Med. 15: 1559–1561. [PubMed]
- 4.Halford J.B.S., Anderson S. D. Tinnitus severity measured bya subjective scale, audiometery and clinical judgement. Journal of Laryngology & Otology. 1991;105:89–93. doi: 10.1017/s0022215100115038. [DOI] [PubMed] [Google Scholar]
- 5.Lobel M. J. Is hearing loss due to nutritional deficiency. Archives of Otolaryngology. 1951;53:515–576. doi: 10.1001/archotol.1951.03750050035003. [DOI] [PubMed] [Google Scholar]
- 6.Yantis P. A. Handbook of Clinical Audiology by Katz. 3rd edition. Baltimore: The William & Wilkins company; 1994. pp. 154–154.. [Google Scholar]