Skip to main content
The Journal of Headache and Pain logoLink to The Journal of Headache and Pain
. 2010 Feb 26;11(3):187–195. doi: 10.1007/s10194-010-0199-y

Relationship between insomnia and headache in community-based middle-aged Hong Kong Chinese women

Wing-Fai Yeung 1, Ka-Fai Chung 1,, Chun-Yue Wong 1
PMCID: PMC3451911  PMID: 20186559

Abstract

Limited studies have investigated the prevalence of insomnia symptoms among individuals with different headache diagnoses and the association between insomnia and headache in subjects with comorbid anxiety and depression. A total of 310 community-dwelling Hong Kong Chinese women aged 40–60 years completed a self-administered questionnaire on headache, sleep difficulties, mood disturbances, and functional impairment. About 31% of the sample complained of recurrent headache unrelated to influenza and the common cold in the past 12 months. The percentages of women diagnosed to have migraine, tension-type headache (TTH), and headache unspecified were 8.4, 15.5 and 7.1%, respectively. The most frequent insomnia complaint was “problem waking up too early” (29.4%), followed by “difficulty staying asleep” (28.0%) and “difficulty falling asleep” (24.4%). Women with headaches were significantly more likely to report insomnia symptoms than those without headaches. There were no significant differences among women with migraine, TTH, and headache unspecified in the prevalence of insomnia symptoms. Logistic regression analysis showed that women with insomnia disorder as defined by an insomnia severity index total score ≥8 had 2.2-fold increased risk of reporting recurrent headache, 3.2-fold increased risk of migraine, and 2.3-fold increased risk of TTH, after adjusting for anxiety and depression. Individual insomnia symptoms were not independent predictors. The association between insomnia and headache was stronger in subjects with more frequent headaches. Our findings suggest that insomnia and the associated distress, but not insomnia symptoms alone, is an independent risk factor for recurrent headache in middle-aged women with mixed anxiety, depression and sleep disturbances.

Keywords: Anxiety, Depression, Headache, Insomnia, Migraine, Tension-type headache

Full Text

The Full Text of this article is available as a PDF (186.9 KB).

Conflict of interest

None.

References

  • 1.Stovner L, Hagen K, Jensen R, Katsarava Z, Lipton R, Scher A, Steiner T, Zwart JA. The global burden of headache: a documentation of headache prevalence and disability worldwide. Cephalalgia. 2007;27:193–210. doi: 10.1111/j.1468-2982.2007.01288.x. [DOI] [PubMed] [Google Scholar]
  • 2.Cheung RT. Prevalence of migraine, tension-type headache, and other headaches in Hong Kong. Headache. 2000;40:473–479. doi: 10.1046/j.1526-4610.2000.00071.x. [DOI] [PubMed] [Google Scholar]
  • 3.Penacoba-Puente C, Fernandez-de-Las-Penas C, Gonzalez-Gutierrez JL, Miangolarra-Page JC, Pareja JA. Interaction between anxiety, depression, quality of life and clinical parameters in chronic tension-type headache. Eur J Pain. 2008;12:886–894. doi: 10.1016/j.ejpain.2007.12.016. [DOI] [PubMed] [Google Scholar]
  • 4.Tietjen GE, Brandes JL, Digre KB, Baggaley S, Martin V, Recober A, Geweke LO, Hafeez F, Aurora SK, Herial NA, Utley C, Khuder SA. High prevalence of somatic symptoms and depression in women with disabling chronic headache. Neurology. 2007;68:134–140. doi: 10.1212/01.wnl.0000251195.55563.02. [DOI] [PubMed] [Google Scholar]
  • 5.Zwart JA, Dyb G, Hagen K, Odegard KJ, Dahl AA, Bovim G, Stovner LJ. Depression and anxiety disorders associated with headache frequency. The Nord-Trondelag Health Study. Eur J Neurol. 2003;10:147–152. doi: 10.1046/j.1468-1331.2003.00551.x. [DOI] [PubMed] [Google Scholar]
  • 6.Pompili M, Cosimo DD, Innamorati M, Lester D, Tatarelli R, Martelletti P. Psychiatric comorbidity in patients with chronic daily headache and migraine: a selective overview including personality traits and suicidal risk. J Headache Pain. 2009;10:283–290. doi: 10.1007/s10194-009-0134-2. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 7.Jensen R, Stovner LJ. Epidemiology and comorbidity of headache. Lancet Neurol. 2008;7:354–361. doi: 10.1016/S1474-4422(08)70062-0. [DOI] [PubMed] [Google Scholar]
  • 8.Boardman HF, Thomas E, Millson DS, Croft PR. Psychological, sleep, lifestyle, and comorbid associations with headache. Headache. 2005;45:657–669. doi: 10.1111/j.1526-4610.2005.05133.x. [DOI] [PubMed] [Google Scholar]
  • 9.Kelman L, Rains JC. Headache and sleep: examination of sleep patterns and complaints in a large clinical sample of migraineurs. Headache. 2005;45:904–910. doi: 10.1111/j.1526-4610.2005.05159.x. [DOI] [PubMed] [Google Scholar]
  • 10.Maizels M, Burchette R. Somatic symptoms in headache patients: the influence of headache diagnosis, frequency, and comorbidity. Headache. 2004;44:983–993. doi: 10.1111/j.1526-4610.2004.04192.x. [DOI] [PubMed] [Google Scholar]
  • 11.Rasmussen BK. Migraine and tension-type headache in a general population: precipitating factors, female hormones, sleep pattern and relation to lifestyle. Pain. 1993;53:65–72. doi: 10.1016/0304-3959(93)90057-V. [DOI] [PubMed] [Google Scholar]
  • 12.Spierings EL, Hoof MJ. Fatigue and sleep in chronic headache sufferers: an age- and sex-controlled questionnaire study. Headache. 1997;37:549–552. doi: 10.1046/j.1526-4610.1997.3709549.x. [DOI] [PubMed] [Google Scholar]
  • 13.Vgontzas A, Cui L, Merikangas KR. Are sleep difficulties associated with migraine attributable to anxiety and depression? Headache. 2008;48:1451–1459. doi: 10.1111/j.1526-4610.2008.01175.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 14.Ohayon MM. Prevalence and risk factors of morning headaches in the general population. Arch Intern Med. 2004;164:97–102. doi: 10.1001/archinte.164.1.97. [DOI] [PubMed] [Google Scholar]
  • 15.Lyngberg AC, Rasmussen BK, Jorgensen T, Jensen R. Prognosis of migraine and tension-type headache: a population-based follow-up study. Neurology. 2005;65:580–585. doi: 10.1212/01.wnl.0000172918.74999.8a. [DOI] [PubMed] [Google Scholar]
  • 16.Lyngberg AC, Rasmussen BK, Jorgensen T, Jensen R. Incidence of primary headache: a Danish epidemiologic follow-up study. Am J Epidemiol. 2005;161:1066–1073. doi: 10.1093/aje/kwi139. [DOI] [PubMed] [Google Scholar]
  • 17.Leger D, Guilleminault C, Dreyfus JP, Delahaye C, Paillard M. Prevalence of insomnia in a survey of 12,778 adults in France. J Sleep Res. 2000;9:35–42. doi: 10.1046/j.1365-2869.2000.00178.x. [DOI] [PubMed] [Google Scholar]
  • 18.Li RH, Wing YK, Ho SC, Fong SY. Gender differences in insomnia—a study in the Hong Kong Chinese population. J Psychosom Res. 2002;53:601–609. doi: 10.1016/S0022-3999(02)00437-3. [DOI] [PubMed] [Google Scholar]
  • 19.Chen CN, Wong J, Lee N, Chan-Ho MW, Lau JT, Fung M. The Shatin community mental health survey in Hong Kong. II. Major findings. Arch Gen Psychiatry. 1993;50:125–133. doi: 10.1001/archpsyc.1993.01820140051005. [DOI] [PubMed] [Google Scholar]
  • 20.Grant BF, Hasin DS, Stinson FS, Dawson DA, June Ruan W, Goldstein RB, Smith SM, Saha TD, Huang B. Prevalence, correlates, co-morbidity, and comparative disability of DSM-IV generalized anxiety disorder in the USA: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Psychol Med. 2005;35:1747–1759. doi: 10.1017/S0033291705006069. [DOI] [PubMed] [Google Scholar]
  • 21.Kalaydjian A, Merikangas K. Physical and mental comorbidity of headache in a nationally representative sample of US adults. Psychosom Med. 2008;70:773–780. doi: 10.1097/PSY.0b013e31817f9e80. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 22.Chung KF, Tang MK. Subjective sleep disturbance and its correlates in middle-aged Hong Kong Chinese women. Maturitas. 2006;53:396–404. doi: 10.1016/j.maturitas.2005.07.001. [DOI] [PubMed] [Google Scholar]
  • 23.Ohayon MM. Severe hot flashes are associated with chronic insomnia. Arch Intern Med. 2006;166:1262–1268. doi: 10.1001/archinte.166.12.1262. [DOI] [PubMed] [Google Scholar]
  • 24.Hodson J, Thompson J, Al-Azzawi F. Headache at menopause and in hormone replacement therapy users. Climacteric. 2000;3:119–124. doi: 10.3109/13697130009167613. [DOI] [PubMed] [Google Scholar]
  • 25.Wang SJ, Fuh JL, Lu SR, Juang KD, Wang PH. Migraine prevalence during menopausal transition. Headache. 2003;43:470–478. doi: 10.1046/j.1526-4610.2003.03092.x. [DOI] [PubMed] [Google Scholar]
  • 26.Bastien CH, Vallieres A, Morin CM. Validation of the insomnia severity index as an outcome measure for insomnia research. Sleep Med. 2001;2:297–307. doi: 10.1016/S1389-9457(00)00065-4. [DOI] [PubMed] [Google Scholar]
  • 27.Smith S, Trinder J. Detecting insomnia: comparison of four self-report measures of sleep in a young adult population. J Sleep Res. 2001;10:229–235. doi: 10.1046/j.1365-2869.2001.00262.x. [DOI] [PubMed] [Google Scholar]
  • 28.American Psychiatric Association (1994) Diagnostic and statistical manual of mental disorders, 4th edn. American Psychiatric Association, Washington, DC
  • 29.Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67:361–370. doi: 10.1111/j.1600-0447.1983.tb09716.x. [DOI] [PubMed] [Google Scholar]
  • 30.International Headache Society The international classification of headache disorders: 2nd edition. Cephalalgia. 2004;24:8–160. doi: 10.1111/j.1468-2982.2003.00824.x. [DOI] [PubMed] [Google Scholar]
  • 31.Sheehan DV, Harnett-Sheehan K, Raj BA. The measurement of disability. Int Clin Psychopharmacol. 1996;11:89–95. doi: 10.1097/00004850-199606003-00015. [DOI] [PubMed] [Google Scholar]
  • 32.Leung CM, Wing YK, Kwong PK, Lo A, Shum K. Validation of the Chinese-Cantonese version of the hospital anxiety and depression scale and comparison with the Hamilton rating scale of depression. Acta Psychiatr Scand. 1999;100:456–461. doi: 10.1111/j.1600-0447.1999.tb10897.x. [DOI] [PubMed] [Google Scholar]
  • 33.Savard MH, Savard J, Simard S, Ivers H. Empirical validation of the insomnia severity index in cancer patients. Psychooncology. 2005;14:429–441. doi: 10.1002/pon.860. [DOI] [PubMed] [Google Scholar]
  • 34.Freeman EW, Sammel MD, Lin H, Gracia CR, Kapoor S. Symptoms in the menopausal transition: hormone and behavioral correlates. Obstet Gynecol. 2008;111:127–136. doi: 10.1097/01.AOG.0000295867.06184.b1. [DOI] [PubMed] [Google Scholar]
  • 35.Wong TW, Wong KS, Yu TS, Kay R. Prevalence of migraine and other headaches in Hong Kong. Neuroepidemiology. 1995;14:82–91. doi: 10.1159/000109782. [DOI] [PubMed] [Google Scholar]
  • 36.Chung KF, Tso KC (2010) Relationship between insomnia and pain in major depressive disorder: a sleep diary and actigraphy study. Sleep Med. doi:10.1016/j.sleep.2009.09.005 [DOI] [PubMed]
  • 37.Buysse DJ, Ancoli-Israel S, Edinger JD, Lichstein KL, Morin CM. Recommendations for a standard research assessment of insomnia. Sleep. 2006;29:1155–1173. doi: 10.1093/sleep/29.9.1155. [DOI] [PubMed] [Google Scholar]
  • 38.Paiva T, Hering-Hanit R. Headache and sleep. In: Olesen J, Tflelt-Hansen P, Welch KM, editors. The headaches. 2. Philadelphia: Lippincott; 2000. pp. 967–973. [Google Scholar]
  • 39.Calhoun AH, Ford S. Behavioral sleep modification may revert transformed migraine to episodic migraine. Headache. 2007;47:1178–1183. doi: 10.1111/j.1526-4610.2007.00780.x. [DOI] [PubMed] [Google Scholar]

Articles from The Journal of Headache and Pain are provided here courtesy of BMC

RESOURCES