Abstract
Psychiatric disorders, notably mood and anxiety disorders, are frequently associated with migraine and chronic daily headaches. The obsessive–compulsive disorder (OCD) is included in the spectrum of anxiety disorders and may be a comorbid condition in headache patients. However, little information has been reported in the literature about this association. This is an important issue as OCD may contribute to the development or maintenance of treatment-resistant chronic headaches. In this paper, we describe a young female patient with refractory chronic migraine and OCD. Considerations on diagnosis, management and treatment of these comorbid conditions are presented.
Keywords: Migraine, Chronic daily headache, Obsessive–compulsive disorder, Psychiatric comorbidity
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Conflict of interest
None.
References
- 1.Juang KD, Wang SJ, Fuh JL, et al. Comorbity of depression and anxiety disorders in chronic daily headache and its subtypes. Headache. 2000;40:818–823. doi: 10.1046/j.1526-4610.2000.00148.x. [DOI] [PubMed] [Google Scholar]
- 2.Radat F, Swendsen J. Psychiatric comorbidy in migraine: a review. Cephalalgia. 2005;25:165–178. doi: 10.1111/j.1468-2982.2004.00839.x. [DOI] [PubMed] [Google Scholar]
- 3.Torelli P, Lambru G, Manzoni GC. Psychiatric comorbidity and headache: clinical and therapeutical aspects. Neurol Sci. 2006;27:S73–S76. doi: 10.1007/s10072-006-0574-2. [DOI] [PubMed] [Google Scholar]
- 4.Guidetti V, Galli FT, Fabrizi P, et al. Headache and psychiatric comorbidity: clinical aspects and outcomes in an 8-year follow-up study. Cephalalgia. 1998;18:455–462. doi: 10.1046/j.1468-2982.1998.1807455.x. [DOI] [PubMed] [Google Scholar]
- 5.Mazzone L, Vitiello B, Incorpora G, Mazzone D. Behavioural and temperamental characteristics of children and adolescents suffering from primary headache. Cephalalgia. 2005;26:194–201. doi: 10.1111/j.1468-2982.2005.01015.x. [DOI] [PubMed] [Google Scholar]
- 6.Pakalnis A, Gibson J, Colvin A. Comorbidity of psychiatric and behavioral disorders in pediatric migraine. Headache. 2005;45:590–596. doi: 10.1111/j.1526-4610.2005.05113.x. [DOI] [PubMed] [Google Scholar]
- 7.Pakalnis A, Butz C, Splaingard D, Kring D, Fong J. Emotional problems and prevalence of medication overuse in pediatric chronic daily headache. J Child Neurol. 2007;22:1356–1359. doi: 10.1177/0883073807307090. [DOI] [PubMed] [Google Scholar]
- 8.Wang SJ, Fuh JL, Lu SR, Juang KD. Outcomes and predictors of chronic daily headache in adolescents: a 2-year longitudinal study. Neurology. 2007;68:591–596. doi: 10.1212/01.wnl.0000252800.82704.62. [DOI] [PubMed] [Google Scholar]
- 9.Baskin SM, Lipchik GL, Smitherman TA. Mood and anxiety disorders in chronic headache. Headache. 2006;46(Suppl 3):S76–S87. doi: 10.1111/j.1526-4610.2006.00559.x. [DOI] [PubMed] [Google Scholar]
- 10.Headache Classification Subcommittee of the IHS (2004) The International Classification of Headache Disorders, 2nd edn. Cephalalgia 24 (Suppl 1):8–160 [DOI] [PubMed]
- 11.Lewis D, Ashwal S, Hershey A, et al. Practice parameter: pharmacological treatment of migraine headache in children and adolescents: report of the American Academy of Neurology Quality Standards Subcommittee and the Practice Committee of the Child Neurology Society. Neurology. 2004;63(12):2215–2224. doi: 10.1212/01.wnl.0000147332.41993.90. [DOI] [PubMed] [Google Scholar]
- 12.American Psychiatric Association (2000) Diagnostic and statistical manual of mental disorders, 4th edn. American Psychiatric Association, Washington, DC
- 13.Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, Hergueta T, Baker R, Dunbar GC. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry. 1998;59(Suppl 20):22–33. [PubMed] [Google Scholar]
- 14.Riva D, Aggio F, Vago C, et al. Cognitive and behavioural effects of migraine in childhood and adolescence. Cephalalgia. 2006;26:596–603. doi: 10.1111/j.1468-2982.2006.01072.x. [DOI] [PubMed] [Google Scholar]
- 15.Sareen J, Jacobi F, Cox BJ, et al. Disability and poor quality of life associated with comorbid anxiety disorders and physical conditions. Arch Intern Med. 2006;166:2109–2116. doi: 10.1001/archinte.166.19.2109. [DOI] [PubMed] [Google Scholar]
- 16.Maizels M, Smitherman TA, Penzien DB. A review of screening tools for psychiatric comorbidity in headache patients. Headache. 2006;46(Suppl 3):S98–S109. doi: 10.1111/j.1526-4610.2006.00561.x. [DOI] [PubMed] [Google Scholar]
- 17.Baskin SM. Managing the “difficult” headache patient. Neurol Sci. 2007;28:S78–S83. doi: 10.1007/s10072-007-0755-7. [DOI] [PubMed] [Google Scholar]
- 18.Savarese M, Guazzelli M, Prudenzano MP, et al. Tertiary treatment for psychiatric comorbidity in headache patients. J Headache Pain. 2005;6:231–233. doi: 10.1007/s10194-005-0193-y. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 19.Lipchik GL, Smitherman TA, Penzien DB, et al. Basic principles and techniques of cognitive-behavioral therapies for comorbid psychiatric symptoms among headache patients. Headache. 2006;46(Suppl 3):S119–S132. doi: 10.1111/j.1526-4610.2006.00563.x. [DOI] [PubMed] [Google Scholar]
- 20.Griffith JL, Razavi M. Pharmacological management of mood and anxiety disorders in headache patients. Headache. 2006;46(Suppl 3):S133–S141. doi: 10.1111/j.1526-4610.2006.00564.x. [DOI] [PubMed] [Google Scholar]
- 21.Bigal ME, Rapoport AM, Sheftell FD, et al. Transformed migraine and medication overuse in a tertiary headache center—clinical characteristics and treatment outcomes. Cephalalgia. 2004;24:483–490. doi: 10.1111/j.1468-2982.2004.00691.x. [DOI] [PubMed] [Google Scholar]
- 22.Thuile J, Even C, Guelfi JD. Topiramate may induce obsessive-compulsive disorder. Psychiatry Clin Neurosci. 2006;60(3):394. doi: 10.1111/j.1440-1819.2006.01520.x. [DOI] [PubMed] [Google Scholar]
- 23.Cohen D. Should the use of selective serotonin reuptake inhibitors in child and adolescent depression be banned? Psychother Psychosom. 2007;76:5–14. doi: 10.1159/000096360. [DOI] [PubMed] [Google Scholar]
- 24.Silberstein SD, Peres MF, Hopkins MM, et al. Olanzapine in the treatment of refractory migraine and chronic daily headache. Headache. 2002;42:515–518. doi: 10.1046/j.1526-4610.2002.02126.x. [DOI] [PubMed] [Google Scholar]
- 25.Boccia G, Del Giucce E, Crrisanti AF, et al. Functional gastrointestinal disorders in migrainous children: efficacy of flunarizine. Cephalalgia. 2006;26(10):1214–1219. doi: 10.1111/j.1468-2982.2006.01196.x. [DOI] [PubMed] [Google Scholar]
- 26.O’Kearney RT, Anstey KJ, Sanden C. Behavioural and cognitive behavioural therapy for obsessive compulsive disorder in children and adolescents. Cochrane Database Syst Rev. 2006;18(4):CD004856. doi: 10.1002/14651858.CD004856.pub2. [DOI] [PMC free article] [PubMed] [Google Scholar]