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The Journal of Headache and Pain logoLink to The Journal of Headache and Pain
. 2010 Jan 9;11(2):167–169. doi: 10.1007/s10194-009-0182-7

Angiotensin II receptor antagonists against migraine in pregnancy: fatal outcome

Kirsti Haaland 1,
PMCID: PMC3452282  PMID: 20063032

Abstract

A pregnant young woman with a severe migraine is prescribed candesartan, an angiotensin II type 1 receptor antagonist (AT II antagonists). This has a positive effect—except for severe maldevelopment of her fetus. There is an increase in the use of the fetotoxic drugs, AT II antagonists and angiotensin-converting enzyme inhibitors, as prophylactic treatment of migraines, in addition to their use as hypertensives.

Keywords: Migraine, Pregnancy, Fetotoxic medication, Angiotensin II receptor antagonist, Angiotensin-converting enzyme inhibitor, Hypertension

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Conflict of interest

None.

Glossary

AT II antagonist

Angiotensin II receptor antagonists

ACE-inhibitors

Angiotensin-converting enzyme inhibitors

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