Abstract
Hemiplegic migraines are characterised by attacks of migraine with aura accompanied by transient motor weakness. There are both familial and sporadic subtypes, which are now recognised as separate entities by the International Classification of Headache Disorders, edition II (ICHD-II). The sporadic subtype has been associated with other medical conditions, particularly rheumatological diseases. We report the case of a woman with sporadic hemiplegic migraine associated with CREST syndrome (calcinosis, Raynaud’s phenomenon, esophageal dysmotility, sclerodactyly and telangiectasia). Since there is a close relationship between migraine and Raynaud’s phenomenon, it could be speculated that the sporadic hemiplegic migraines in our patient might be secondary to CREST syndrome.
Keywords: Migraine disorders, Hemiplegic migraine, Migraine with auras, CREST syndrome
Full Text
The Full Text of this article is available as a PDF (115.5 KB).
Acknowledgments
The authors would like to thank Dr. Pablo A. López, Dr. Francisco Paulin and Dr. María Elina Grecco for their collaboration. Dr. Figuerola is Senior Researcher from CONICET.
Conflict of interest
None.
References
- 1.Headache Classification Subcommittee of the International Headache Society (2004) The International Classification of Headache Disorders, 2nd edn. Cephalalgia 24 (Suppl 1):9–160 [DOI] [PubMed]
- 2.Thomsen LL, Ducros A. Sporadic and familial hemiplegic migraines. In: Olesen J, Tfelt-Hansen P, Goadsby P, editors. The headaches. 3. Philadelphia: Lippincott, Williams and Wilkins; 2005. pp. 583–585. [Google Scholar]
- 3.Vetvik KR, Dahl M, Russell MB. Symptomatic sporadic hemiplegic migraine. Cephalalgia. 2005;25:1093–1095. doi: 10.1111/j.1468-2982.2005.00975.x. [DOI] [PubMed] [Google Scholar]
- 4.Thomsen LL, Olesen J. Sporadic hemiplegic migraine. Cephalalgia. 2004;12:1016–1023. doi: 10.1111/j.1468-2982.2004.00788.x. [DOI] [PubMed] [Google Scholar]
- 5.Thomsen LL, Eriksen M, Faerch S, et al. An epidemiological survey of hemiplegic migraine. Cephalalgia. 2002;5:361–375. doi: 10.1046/j.1468-2982.2002.00371.x. [DOI] [PubMed] [Google Scholar]
- 6.Bhatia R, Desai S, Tripathi M, et al. Sporadic hemiplegic migraine: report of a case with clinical and radiological features. J Headache Pain. 2008;6:385–388. doi: 10.1007/s10194-008-0067-1. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 7.Varga, J (2008) Systemic sclerosis (scleroderma) and related disorders. In: Fauci A, Braunwald E, Kasper D et al (eds) Harrison’s principles of internal medicine, 17th edn. McGraw–Hill, pp 2096–2106
- 8.Kaiser RS. “Raynaud’s disease” in migraineurs: one entity or two? Headache. 1992;32(9):463–465. doi: 10.1111/j.1526-4610.1992.hed3209463_b.x. [DOI] [PubMed] [Google Scholar]
- 9.Geraud G, Fabre N, Soulages X, et al. Migraine and the idiopathic Raynaud phenomenon. Rev Neurol (Paris) 1986;142:638–640. [PubMed] [Google Scholar]
- 10.Zahavi I, Chagnac A, Hering R, et al. Prevalence of Raynaud’s phenomenon in patients with migraine Arch Intern Med 19841444742–744.10.1001/archinte.144.4.742 [PubMed] [Google Scholar]
- 11.Bernatsky S, Pineau CA, Lee JL, Clarke AE. Headache, Raynaud’s syndrome and receptor agonists in systemic lupus erythematosus. Lupus. 2006;12:671–674. doi: 10.1177/0961203306069997. [DOI] [PubMed] [Google Scholar]
- 12.Gabrielli A, Awedimento EV, Krieg T. Scleroderma. N Engl J Med. 2009;360(19):1989–2003. doi: 10.1056/NEJMra0806188. [DOI] [PubMed] [Google Scholar]
