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. 2009 Aug 11;8(2):188–191. doi: 10.1007/s12663-009-0046-3

Ramsay-Hunt syndrome complicating osteonecrosis of edentulous maxilla and mandible: report of a rare case

Samprati J Badjate 1,4,✉, K M Cariappa 2, S R Shenoi 3, Shweta Nakhate 3
PMCID: PMC3453949  PMID: 23139504

Abstract

Review of literature revealed atleast 30 cases of post herpes zoster osteonecrosis of maxilla or mandible. To our knowledge this is a first reported case of Ramsay-Hunt syndrome with post herpetic neuralgia and post herpes zoster osteonecrosis of edentulous maxilla and mandible. We have briefly reviewed the pathophysiology and management of post herpes zoster osteonecrosis and post herpetic neuralgia.

Keywords: Herpes zoster, Ramsay-Hunt syndrome, Osteonecrosis, Maxilla, Mandible, Post herpetic neuralgia

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References

  • 1.Cooper J.C. Tooth exfoliation and osteonecrosis of the jaw following herpes zoster. Br Dent J. 1977;143(9):297–300. doi: 10.1038/sj.bdj.4803994. [DOI] [PubMed] [Google Scholar]
  • 2.Denny-Brown D., Adams R.D., Fitzgerald P.J. Pathologic features of herpes zoster. Arch of Neurol Psychiat. 1994;51:216. [Google Scholar]
  • 3.Barret A.P. Herpes zoster virus infection: A clinicopathologic review and case reports. Aust Dent J. 1990;35(4):328–332. doi: 10.1111/j.1834-7819.1990.tb00780.x. [DOI] [PubMed] [Google Scholar]
  • 4.Hess T.M., Lutz L.J., Nauss L.A., Lamer T.J. Treatment of acute herpetic neuralgia: A case report and review of the literature. Minn med. 1990;73(4):37–40. [PubMed] [Google Scholar]
  • 5.Federico F., Pedone D., Lamberti P., Achille P., Camicia M., Carella A., Ferrari E. Ophthalmic herpes zoster with contralateral hemiparesis: A case report. J Neurol. 1982;228(4):283–287. doi: 10.1007/BF00313419. [DOI] [PubMed] [Google Scholar]
  • 6.Scharf Y., Kraus E., Zonis S. Optic neuropathy and central retinal artery occlusion in a case of herpes zoster ophthalmicus. Ann Ophthalmol. 1987;19(2):77–78. [PubMed] [Google Scholar]
  • 7.McKenna K.F., Wreneke L.B. Encaphalitis associated with herpes zoster: A case report and review. Can J Psychiatry. 1992;37(2):271–273. doi: 10.1177/070674379203700412. [DOI] [PubMed] [Google Scholar]
  • 8.Puskas M., Schneider I., Dull G., Zombai E. Calcinosis post zosterienne. Ann Dermatol Venereol. 1995;122(6–7):436–438. [PubMed] [Google Scholar]
  • 9.Gregory W.B., Jr, Brooks L.E., Penich E.C. Herpes zoster associated with pulpless teeth. J Endod. 1975;1(1):32–35. doi: 10.1016/S0099-2399(75)80248-2. [DOI] [PubMed] [Google Scholar]
  • 10.Goon W.W., Jacobsen P.L. Prodromal odontalgia and multiple devitalized teeth caused by herpes zoster infection of the trigeminal nerve: Report of case. J Am Dent Assoc. 1988;116(4):500–504. doi: 10.14219/jada.archive.1988.0301. [DOI] [PubMed] [Google Scholar]
  • 11.Smith S., Ross J.W., Scully C. An unusal oral complication of herpes zoster infection. Oral Surg Oral Med Oral Pathol. 1984;57(4):388–389. doi: 10.1016/0030-4220(84)90156-7. [DOI] [PubMed] [Google Scholar]
  • 12.Solomon C.S., Coffiner M.O., Chalfin H.E. Herpes Zoster revisited: implicated in root resorption. J Endod. 1986;12(5):210–213. doi: 10.1016/S0099-2399(86)80157-1. [DOI] [PubMed] [Google Scholar]
  • 13.Hall H.D., Jacobs J.S., O’Malley J.P. Necrosis of maxilla in patient with herpes zoster: report of a case. Oral Surg Oral Med Oral Pathol. 1974;37(5):657–662. doi: 10.1016/0030-4220(74)90128-5. [DOI] [PubMed] [Google Scholar]
  • 14.Chenitz J.E. Herpes zoster in Hodgkin’s disease: unusal oral sequelae. ASDC J Dent Child. 1976;43(3):184–186. [PubMed] [Google Scholar]
  • 15.Wright W.E., Davis M.L., Geffen Martin S.E., Nelson M.J., Stratus S.E. Alveolar bone necrosis and tooth loss: a rare complicationassociated with herpes zoster infection of the fifth cranial nerve. Oral Surg Oral Med Oral Pathol. 1983;56(1):39–46. doi: 10.1016/0030-4220(83)90053-1. [DOI] [PubMed] [Google Scholar]
  • 16.Garty B.Z., Dinari G., Sarnath H., Cohen S., Nitzan M. Tooth exfoliation and osteonecrosis of the maxilla after trigeminal herpes zoster. J Pediatr. 1985;106(1):71–73. doi: 10.1016/S0022-3476(85)80469-8. [DOI] [PubMed] [Google Scholar]
  • 17.Muto T., Tsuchiya H., Sato K., Kanazawa M. Tooth exfoliation and necrosis of the mandible — a rare complication following trigeminal herpes zoster: a report of a case. J Oral Maxillofacial Surg. 1990;48(9):1000–1003. doi: 10.1016/0278-2391(90)90020-3. [DOI] [PubMed] [Google Scholar]
  • 18.Pogrel M.A., Miller C.E. A case of maxillary necrosis. J Oral Maxillofac Surg. 2003;61(4):489–493. doi: 10.1053/joms.2003.50095. [DOI] [PubMed] [Google Scholar]
  • 19.Waterman G., Epstein J.D., Fenske N.A. Herpes zoster infection with trigeminal and facial nerve involvement. Cutis. 1989;43(3):262–263. [PubMed] [Google Scholar]
  • 20.Braunwald G., editor. Harrisons Principles of internal Medicine (ed 12) New York, NY: McGraw-Hill; 1991. p. 687. [Google Scholar]
  • 21.Weatherall D.J., et al. Oxford textbook of medicine (ed Int) Oxford United Kingdom: Oxford University Press; 1984. [Google Scholar]
  • 22.Hudson C.D., Vickers R.A. Clinicopathologic observations in prodromal herpes zoster of the fifth cranial nerve: Report of a case. Oral Surg Oral Med Oral Pathol. 1971;31(4):494–501. doi: 10.1016/0030-4220(71)90346-X. [DOI] [PubMed] [Google Scholar]
  • 23.Dirbas F.M., Swain J.A. Disseminated cutaneous herpes zoster following cardiac surgery. J Cardio Surg. 1990;31(4):531–532. [PubMed] [Google Scholar]
  • 24.Flood D.A., Chan C.K., Pruzanski W. Pneumocystis carinii pneumonia associated with methotrexate therapy in rheumatoid arthritis. J Rheumatology. 1991;18(8):1254–1256. [PubMed] [Google Scholar]
  • 25.Beeson P.B., et al. Textbook of Medicine (ed 15) Philadelphia, PA: Saunders; 1979. p. 824. [Google Scholar]
  • 26.Barrett A.P., Katelaris C.H., Morris J.G., Schifter M. Zoster sine herpete of the trigeminal nerve. Oral Surg Oral Med Oral Pathol. 1993;75(2):173–175. doi: 10.1016/0030-4220(93)90089-M. [DOI] [PubMed] [Google Scholar]
  • 27.Furguson R.H. Vasculitis associated with herpes zoster. Mayo clin Proc. 1981;56:524–525. [Google Scholar]
  • 28.Seltzer S., Bender I.B., editors. The dental pulp. 2. Philadelphia: JB Lippincott; 1975. p. 95. [Google Scholar]
  • 29.Mintz S.M., Anavi Y. Maxillary osteomyelitis and spontaneous tooth exfoliation after herpes zoster. Oral Surg Oral Med Oral Pathol. 1992;73(6):664–666. doi: 10.1016/0030-4220(92)90005-B. [DOI] [PubMed] [Google Scholar]
  • 30.Hope-Simpson R.E. Postherpetic neuralgia. J R Coll Gen Pract. 1975;25(157):571–575. [PMC free article] [PubMed] [Google Scholar]
  • 31.Brown G.R. Herpes zoster: correlation of age, sex, distribution, neuralgia, and associated disorders. South Med J. 1976;69(5):576–578. [PubMed] [Google Scholar]
  • 32.Nurkkimo T.J., Rasanan A., Hakkien V. Clinical and neurophysiological observations on acute herpes zoster. Clin J pain. 1990;6(4):284–290. doi: 10.1097/00002508-199012000-00005. [DOI] [PubMed] [Google Scholar]
  • 33.Bonica J.J. The management of pain. 2. Philadelphia: Lea and Febiger; 1990. [Google Scholar]
  • 34.Portenoy R.K., Duma C., Foley K.M. Acute herpetic and postherpetic neuralgia: clinical review and current management. Ann Neurol. 1986;20(6):651–664. doi: 10.1002/ana.410200602. [DOI] [PubMed] [Google Scholar]
  • 35.Watson C.P.N. Herpes zoster and postherpetic neuralgia. Vol. 8 of Pain research and clinical management. Amsterdam: Elsevier; 1993. [Google Scholar]
  • 36.Bowsher D. Post-herpetic neuralgia in older patients: incidence and optimal treatment. Drugs Aging. 1994;5(6):411–418. doi: 10.2165/00002512-199405060-00003. [DOI] [PubMed] [Google Scholar]
  • 37.Kost R.G., Straus S.E. Post herpetic neuralgia — pathogenesis, treatment, and prevention. N Engl J Med. 1996;335(1):32–42. doi: 10.1056/NEJM199607043350107. [DOI] [PubMed] [Google Scholar]
  • 38.Raj P. Management of herpes zoster pain and post herpetic neuralgia. Pain Digest. 1992;2:201–212. [Google Scholar]
  • 39.Epstein J.B., Marcoe J.H. Topical application of capsaicin for treatment of oral Neuropathic pain and trigeminal neuralgia. Oral Surg Oral Med Oral Pathol. 1994;77(2):135–140. doi: 10.1016/0030-4220(94)90275-5. [DOI] [PubMed] [Google Scholar]
  • 40.Kishore Kumar R., Max M.B., Schafer S.C., Gaughan A.M., Smoller B., Gracely R.H., Dubner R. Desipramine relieves post herpetic neuralgia. Clin Pharmacol Ther. 1990;47(3):305–312. doi: 10.1038/clpt.1990.33. [DOI] [PubMed] [Google Scholar]
  • 41.Rosenberg J.M., Harrell C., Ristic H., Werner R.A., Rosayro A.M. The effect of gabapentine on Neuropathic pain. Clin J Pain. 1997;13(3):251–255. doi: 10.1097/00002508-199709000-00011. [DOI] [PubMed] [Google Scholar]
  • 42.Davis K.D., Treede R.D., Raja S.N., Meyer R.A., Campbell J.N. Topical application of clonidine relieves hyperalgesia in patients with sympathetically maintained pain. Pain. 1991;47(3):309–317. doi: 10.1016/0304-3959(91)90221-I. [DOI] [PubMed] [Google Scholar]
  • 43.Rowbotham M.C., Davies P.S., Verkempinck C., Galer B.S. Lidocaine patch: Double blind controlled study of a new treatment method for post herpetic neuralgia. Pain. 1996;65(1):39–44. doi: 10.1016/0304-3959(95)00146-8. [DOI] [PubMed] [Google Scholar]

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