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. 2010 Apr 24;8(4):301–307. doi: 10.1007/s12663-009-0074-z

Efficacy of platelet rich plasma in bone regeneration after surgical removal of impacted bilateral mandibular third molars: pilot study

Pushkar D Gawande 1,2,✉, Rajshekhar Halli 1
PMCID: PMC3454101  PMID: 23139532

Abstract

Purpose

This study was done to assess the efficacy of platelet rich plasma (PRP) in bone regeneration.

Materials and methods

20 patients having bilateral mandibular third molar impaction with similar angulations were included in the present study. The extraction socket was packed with PRP on one side and the other side was sutured without PRP. The bone density of both extraction sockets were evaluated radiographically using gray level histogram and compared periodically. Postoperative pain and edema were also assessed.

Results

The result of the study shows rapid bone regeneration in the extraction socket treated with PRP when compared with the socket without PRP. Also there was less postoperative discomfort on the PRP treated side.

Conclusion

Within the limits of the present study it can be concluded that usage of PRP expedites bone regeneration, and reduces postoperative complications.

Keywords: Platelet rich plasma, Growth factors, Third molar, Bone regeneration

Full Text

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