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References
- 1.Berger EA, Murphy PM, Farber JM. Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease. Ann. Rev. Immunol. 1999;17:657–700. doi: 10.1146/annurev.immunol.17.1.657. [DOI] [PubMed] [Google Scholar]
- 2.Alkhatib G, Combadiere C, Broder CC, Feng Y, Kennedy PE, Murphy PM, Berger EA. CC CKR5: α RANTES, MIP-1α, MIP-1β receptor as a fusion cofactor for macrophage-tropic HIV-1. Science. 1996;272:1955–1958. doi: 10.1126/science.272.5270.1955. [DOI] [PubMed] [Google Scholar]
- 3.Berson JF, Long D, Doranz GJ, Rucker J, Jirik FR, Doms RW. A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains. J. Virol. 1996;70:6288–6295. doi: 10.1128/jvi.70.9.6288-6295.1996. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 4.He J, Farzan M, Choe H, Ohagen A, Gartner S, Busciglio J, Yang X, Hofmann W, Newman W, Mackay RC, Sodroski J, Gabuzda D. CCR3 and CCR5 are coreceptors for HIV-1 infection of microglia. Nature. 1997;385:645–649. doi: 10.1038/385645a0. [DOI] [PubMed] [Google Scholar]
- 5.Edinger AL, Clements EJ, Doms RW. Chemokine and orphan receptors in HIV-2 and SIV tropism and pathogenesis. Virology. 1999;260:211–221. doi: 10.1006/viro.1999.9819. [DOI] [PubMed] [Google Scholar]
- 6.Liu R, Paxton WA, Choe S, Ceradini D, Martin RS, Horuk R, Macdonald EM, Stuhlmann H, Koup RA, Landau NR. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply exposed individuals to HIV-1 infection. Cell. 1996;86:367–377. doi: 10.1016/S0092-8674(00)80110-5. [DOI] [PubMed] [Google Scholar]
- 7.Biti R, Ffrench R, Young J, Bennets B, Stewart G. HIV-1 infection in an individual homozygous for the CCR5 deletion allele. Nature Medicine. 1997;3:252–253. doi: 10.1038/nm0397-252. [DOI] [PubMed] [Google Scholar]
- 8.Michael NL, Nelson JAE, Kewalramani VN, Chang G, O'Brien SJ, Mascola JR, Volsky B, Louder M, White GC, Littman DR, Swanstrom R, O'Brien TR. Exclusive and persistent use of the entry coreceptor CXCR4 by human immunodeficiency virus type 1 from a subject homozygous forCCR5D32. J. Virol. 1998;72:6040–6047. doi: 10.1128/jvi.72.7.6040-6047.1998. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 9.Samson M, Libert F, Doranj B, Rucker J, Liesnard C, Farber C-M, Sargosti S, Lapoumeroulie C, Cognaux J. Resistance to HIV-1 infection in Caucasion individuals bearing mutant alleles of CCR5 chemokine receptor gene. Nature. 1996;382:722–725. doi: 10.1038/382722a0. [DOI] [PubMed] [Google Scholar]
- 10.Huang Y, Paxton WA, Wolinsky SM, Neumann AU, Zhang L. The role of mutant CCR5 allele in HIV-1 transmission and disease progression. Nature Medicine. 1996;2:1240–1243. doi: 10.1038/nm1196-1240. [DOI] [PubMed] [Google Scholar]
- 11.Husain S, Goila R, Shahi S, Banerjea AC. First report of a healthy Indian heterozygous for D32 mutant of HIV-1 coreceptor-CCR5 gene. Gene. 1998;207:141–147. doi: 10.1016/S0378-1119(97)00617-3. [DOI] [PubMed] [Google Scholar]
- 12.Husain S, Goila R, Shahi S, Banerjea AC. Inheritance pattern of mutant human immunode virus type 1 coreceptor gene in an Indian family. J. Human Virol. 1998;1:187–192. [PubMed] [Google Scholar]
- 13.Mummidi S, Ahuja SS, Gonzales E, Anderson SA, Santiago EN, Stephan KT, Craig FE, O'Connell P, Tryon V, Clark RA, Dolan MJ, Ahuja SK. Genealogy of the CCR5 locus and chemokine system gene variants associated with altered rates of HIV-1 disease progression. Nature Medicine. 1998;4:786–793. doi: 10.1038/nm0798-786. [DOI] [PubMed] [Google Scholar]
- 14.Winkler C, Modi W, Smith MW. Genetic restriction of AIDS pathogenesis by an SDF-1 chemokine gene variant. Science. 1998;279:389–393. doi: 10.1126/science.279.5349.389. [DOI] [PubMed] [Google Scholar]
- 15.Banerjea AC (2000) Role of host factors in progression of HIV-1. In the Ranbaxy Science Foundation's Round Table Conference on HIV/AIDS in India, New Delhi.
- 16.Kostrikis LG, Huang Y, Moore JP, Wolinsky SM, Zhang L, Guo Y, Deutsch L, Phair J, Neumann AU, Ho DD. A chemokine receptor CCR2 allele delays HIV-1 disease progression and is associated with a CCR5 promoter mutation. Nature Medicine. 1998;3:350–353. doi: 10.1038/nm0398-350. [DOI] [PubMed] [Google Scholar]
- 17.Lole KS, Bollinger RC, Raranjape RS, Gadkari D, Kulkarni SS, Novak NG, Ingersoll R, Sheppard HW, Ray SC. Full-length human immunodeficiency virus type 1 genomes from subtype C infected seroconverters in India, with evidence of intersubtype recombination. J. Virol. 1999;73:152–160. doi: 10.1128/jvi.73.1.152-160.1999. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 18.Goila R, Banerjea AC. Sequence specific cleavage of HIV-1 coreceptor-CCR5 gene by a hammerhead ribozyme and a DNA-enzyme. Inhibition of the coreceptor function by DNA-enzymes. FEBS Letters. 1998;436:233–238. doi: 10.1016/S0014-5793(98)01137-5. [DOI] [PubMed] [Google Scholar]
- 19.Dash BC, Harikrishnan TA, Goila R, Shahi S, Unwalla H, Husain S, Banerjea AC. Targeted cleavage of HIV-1 envelope gene by a DNA-enzyme and inhibition of HIV-1 envelope-CD4 mediated cell fusion. FEBS Letters. 1998;431:395–399. doi: 10.1016/S0014-5793(98)00799-6. [DOI] [PubMed] [Google Scholar]
- 20.Ramamoorti N, Banerjea AC. Novel SDF-1 gene mutations in simians: presence of GG-AA transition in the 3′ untranslated region. AIDS. 2000;14:1279–1281. doi: 10.1097/00002030-200006160-00029. [DOI] [PubMed] [Google Scholar]
- 21.Shanmugasundaram GK, Ramamoorti N, Banerjea AC. Novel HIV-1 co-receptor-CCR5 promoter mutations in simians: identification of two highly polymorphic regions with extensive deletions. AIDS. 2000;14:2201–2202. doi: 10.1097/00002030-200009290-00017. [DOI] [PubMed] [Google Scholar]
- 22.Ramamoorti N, Goila R, Banerjea AC. Extensive polymorphism in RANTES promoter of Bonnet, Baboon and Rhesus monkeys. AIDS. 2000;14:2401–2403. doi: 10.1097/00002030-200010200-00022. [DOI] [PubMed] [Google Scholar]