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Indian Journal of Clinical Biochemistry logoLink to Indian Journal of Clinical Biochemistry
. 2005 Jan;20(1):85–86. doi: 10.1007/BF02893048

Effect of vitamin A supplementation on hematopoiesis in children with anemia

Arun Garg 1,, Pankaj Abrol 1, AD Tewari 1, Rajiv Sen 2, Harbans Lal 3,
PMCID: PMC3454151  PMID: 23105500

Abstract

Fifty children (1–4 years age) presenting with microcytic hypochromic anemia (hemoglobin less than 10g/dl) were studied in two groups of 25 each. Group I was supplemented with iron (ferrous sulphate 6 mg/kg/d) while group II in addition to iron was also supplemented with vitamin A (5000 IU/d). Hemoglobin concentration was found to be significantly increased after 4 weeks of iron supplementation. Rise in hemoglobin was comparatively more in-group II, as compared to group I, after 8 and 12 weeks. Serum iron was significantly higher after 4 weeks in both the groups. Packed cell volume (PCV) and retinol levels increased significantly in-group II only. The data suggests that supplementation of vitamin A improves hematopoiesis.

Key Words: Vitamin A, Hematopoiesis, Anemia

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