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. 2004 Jul;19(2):111–113. doi: 10.1007/BF02894267

1, 25-Dihydroxycholecalciferol (1,25-(OH)2 D3) levels in osteoporosis

A P S Narang 1,✉, S Batra 2, S Sabharwal 2, S C Ahuja 2
PMCID: PMC3454195  PMID: 23105466

Abstract

In the present study primary involution osteoporosis and vitamin D levels were studied in 60 subjects including thirty controls. The biochemical analysis of serum calcium, phosphorus, ALP, albumin and vitamin D3 (1,25-(OH)2 D3) levels were significantly decreased in osteoporotic patients when compared to non-osteoporotic control group. There was a significant correlation of magnitude of sun exposure with 1,25-(OH)2 D3 levels. Similarly, vitamin D intake in the diet has a significant correlation with 1,25-(OH)2 D3 concentration. However, no correlation could be obtained between vitamin D3 levels with increasing age. Among the biochemical markers serum calcium, phosphorus, ALP and albumin could not be correlated with 1,25-(OH)2 D3 levels.

Keywords: Osteoporosis 1, 25-Dihydroxycholecalciferol

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