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. 1997 Jun;14(6):347–353. doi: 10.1007/BF02765840

Is there really a decrease in sperm parameters among healthy young men? A survey of sperm donations during 15 years

Abraham Benshushan 1,✉, Orly Shoshani 1, Ora Paltiel 2, Joseph G Schenker 1, Aby Lewin 1
PMCID: PMC3454797  PMID: 9226515

Abstract

Purpose: Our purpose was to measure changes in semen quality and quantity in young healthy sperm donors in Jerusalem over time.

Methods: A retrospective analysis of semen parameters over 15 years using linear regression analysis, in a single sperm bank in a tertiary university center. Study population consisted of 188 young, healthy medical students, aged 20 to 30 years, who donated sperm samples for Artificial insemination between 1980 and 1995.

Results: There were no statistically significant changes in semen concentration and motility during the study period. The mean semen volume increased by 0.1 ml (5.1%) per year (P < 0.0001), with a concomitant mean rise of 5.8 × 106 (7.7%) per year in total motile sperm count. The percentage normal morphology decreased by a mean of 1.04% per year during the entire period (P < 0.0001).

Conclusions: During the past 15 years, there has been an increase in total motile sperm count, secondary to an increase in semen volume, and a decline in normal morphology that are independent of the age and the duration of abstinence in fertile men.

Key Words: geographic and time trend, semen concentration, semen morphology, sperm volume

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References

  • 1.Macomber D, Sanders M. The spermatozoa count: Its value in the diagnosis, prognosis and treatment of sterility. Engl J Med. 1929;200:981–984. doi: 10.1056/NEJM192905092001905. [DOI] [Google Scholar]
  • 2.MacLeod J, Gold RZ. The male factor in fertility and infertility II. Spermatozoon counts in 1,000 men of known fertility and in 1,000 cases of infertile marriage. J Urol. 1951;66:436–448. doi: 10.1016/S0022-5347(17)74358-3. [DOI] [PubMed] [Google Scholar]
  • 3.Nelson CMK, Bunge RG. Semen analysis. Evidence for changing parameters of male fertility potential. Fertil Steril. 1974;25:503–507. doi: 10.1016/s0015-0282(16)40454-1. [DOI] [PubMed] [Google Scholar]
  • 4.Naghma-E-Rehan, Sobrero AJ, Fertig JW. The semen of fertile men: statistical analysis of 1300 men. Fertil Steril. 1975;26:492–502. doi: 10.1016/s0015-0282(16)41169-6. [DOI] [PubMed] [Google Scholar]
  • 5.Sheriff DS. Setting standards for male fertility. I. Semen analysis in 1500 patients—a report. Andrologia. 1983;15:687–692. doi: 10.1111/j.1439-0272.1983.tb00194.x. [DOI] [PubMed] [Google Scholar]
  • 6.Wang C, Chan SYW, Leung A, Ng RP, Ng M, Tang LCH. Cross-sectional study of semen parameters in a large group of normal Chinese men. Int J Androl. 1985;8:257–274. doi: 10.1111/j.1365-2605.1985.tb00840.x. [DOI] [PubMed] [Google Scholar]
  • 7.Kirei BR. Semen characteristics in 120 fertile Tanzanian men. East Afr Med J. 1987;64:453–457. [PubMed] [Google Scholar]
  • 8.Carlesen E, Giwercman A, Keiding N, Skakkebaek NE. Evidence for decreasing quality of semen during the past 50 years. BMJ. 1992;305:609–613. doi: 10.1136/bmj.305.6854.609. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 9.Bostofte E, Serup J, Rebbe H. Has the fertility of Danish men declined through the years in terms of semen quality? Int J Fertil. 1983;28:91–95. [PubMed] [Google Scholar]
  • 10.Leto S, Frensilli FJ. Changing parameters of donor semen. Fertil Steril. 1981;36:766–770. doi: 10.1016/s0015-0282(16)45923-6. [DOI] [PubMed] [Google Scholar]
  • 11.Auger J, Kuntsmann JM, Czyglik F, Jouannet P. Decline in semen quality among fertile men in Paris during the last 20 years. Engl NJ Med. 1995;332:281–285. doi: 10.1056/NEJM199502023320501. [DOI] [PubMed] [Google Scholar]
  • 12.Iryine S, Cawood E, Richardson D, MacDonald E, Aitken J. Evidence of deteriorating semen quality in the United Kingdom: Birth cohort study in 577 men in Scotland over 11 years. BMJ. 1997;312:467–470. doi: 10.1136/bmj.312.7029.467. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 13.Fish H, Goluboff ET, Olson JH, Feldshuh J, Broder SJ, Barad DH. Semen analysis in 1,283 men from the United States over a 25-year period. no decline in quality. Fertil Steril. 1995;65:1009–1014. doi: 10.1016/s0015-0282(16)58278-8. [DOI] [PubMed] [Google Scholar]
  • 14.Paulsen CA, Berman NG, Wang C. Data from men in greater Seattle area reveals no downward trend in semen quality: Further evidence that deterioration in semen quality is not geographically uniform. Fertil Steril. 1995;65:1015–1020. [PubMed] [Google Scholar]
  • 15.Fish H, Goluboff ER. Geographic variations in sperm count: A potential cause in bias in semen quality. Fertil Steril. 1995;65:1044–1046. doi: 10.1016/s0015-0282(16)58284-3. [DOI] [PubMed] [Google Scholar]
  • 16.Bujan L, Mansat A, Pontonnier F, Miusset R. Time sereies analysis of sperm concentration in fertile men in Toulouse, France between 1977 and 1992. BMJ. 1997;312:471–472. doi: 10.1136/bmj.312.7029.471. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 17.Schwartz D, Mayaux M-J, Spira A, Moscato M-L, Jouannet P, Czyglik E. Semen characteristics as a function of age in 833 fertile men. Fertil Steril. 1983;39:530–535. doi: 10.1016/s0015-0282(16)46946-3. [DOI] [PubMed] [Google Scholar]
  • 18.Jouannet P, Czyglik F, David G, et al. Study of a group of 484 men. Distribution of semen characteristics. Int J Androl. 1981;4:440–449. doi: 10.1111/j.1365-2605.1981.tb00728.x. [DOI] [PubMed] [Google Scholar]
  • 19.Suominen J, Vierula M. Semen quality of Finnish men. BMJ. 1993;306:1579–1579. doi: 10.1136/bmj.306.6892.1579. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 20.Tummon IS, Mortimer D. Decreasing quality of semen. BMJ. 1992;305:1228–1229. doi: 10.1136/bmj.305.6863.1228-c. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 21.Brake A, Krause W. Decreasing quality of semen. BMJ. 1992;305:1498–1498. doi: 10.1136/bmj.305.6867.1498-b. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 22.Macleod J, Wang Y. Male fertility potential in terms of semen quality: A review of the past, a study of the present. Fertil Steril. 1979;31:103–116. doi: 10.1016/s0015-0282(16)43808-2. [DOI] [PubMed] [Google Scholar]
  • 23.Ginsburg J, Okolo S, Prelevic G, Hardiman P. Residence in the London area and sperm density. Lancet. 1994;343:230–230. doi: 10.1016/S0140-6736(94)91012-X. [DOI] [PubMed] [Google Scholar]
  • 24.Giwercman A, Carlesen E, Keiding N, Skakkebaek NE. Evidence for increasing incidence of abnormalities of the human testis: A review. Environ Health Perspect. 1993;101(Suppl 2):65–71. doi: 10.2307/3431378. [DOI] [PMC free article] [PubMed] [Google Scholar]

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