Abstract
Purpose: In this study, the method of employing pre-retrieval vaginal douching with aqueous povidone iodine is examined to see if it can decrease the incidence of pelvic abscess without compromising the clinical outcome of IVF-ET.
Methods: Patients with ovarian endometrioma and received IVF-ET treatment were retrospectively classified into two groups according to the difference of vaginal douching solution immediately before oocyte retrieval.
Results: There was no difference in the fertilization rate (81.2% versus 79.8%, P > 0.05), implantation rate (19.2% versus 23.3%, P > 0.05), clinical pregnancy rate (39.3% versus 46.2%, P > 0.05) between the two groups. There was no infection in patients of group two but two cases in group one developed pelvic abscess and needed surgical intervention.
Conclusions: Vaginal douching with aqueous povidone iodine followed by normal saline irrigation immediately before oocyte retrieval is effective in preventing the pelvic infection without compromising the outcome of IVF treatment.
Keywords: Endometrioma, in vitro fertilization, infection, pelvic abscess, complication
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References
- 1.Dicker D, Ashkenazi J, Feldberg D, Levy T, Dekel A, Ben-Rafael Z. Severe abdominal complications after transvaginal ultrasonographically guided retrieval of oocytes for in vitro fertilization and embryo transfer. Fertil Steril. 1993;59:1313–1315. doi: 10.1016/s0015-0282(16)55997-4. [DOI] [PubMed] [Google Scholar]
- 2.Bennett SJ, Waterstone JJ, Cheng WC, Parsons J. Complications of transvaginal ultrasound-directed follicle aspiration: a review of 2670 consecutive procedures. J Assist Reprod Genet. 1993;10:72–77. doi: 10.1007/BF01204444. [DOI] [PubMed] [Google Scholar]
- 3.Padilla SL. Ovarian abscess following puncture of an endometrioma during ultrasound-guided oocyte retrieval. Hum Reprod. 1993;8:1282–1283. doi: 10.1093/oxfordjournals.humrep.a138241. [DOI] [PubMed] [Google Scholar]
- 4.Younis JS, Ezra Y, Laufer N, Ohel G. Late manifestation of pelvic abscess following oocyte retrieval, for in vitro fertilization, in patients with severe endometriosis and ovarian endometriomata. J Assist Reprod Genet. 1997;14:343–346. doi: 10.1007/BF02765839. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 5.Tsai YC, Chung MT, Sung YH, Tsai TF, Tsai YT, Lin LY. Clinical value of early cleavage embryo. Int J Gynecol Obstet. 2002;F76(3):293–297. doi: 10.1016/s0020-7292(01)00591-4. [DOI] [PubMed] [Google Scholar]
- 6.Howe RS, Wheeler C, Mastroianni L, Jr, Blasco L, Tureck R. Pelvic infection after transvaginal ultrasound-guided ovum retrieval. Fertil Steril. 1988;49:726–728. doi: 10.1016/s0015-0282(16)59849-5. [DOI] [PubMed] [Google Scholar]
- 7.Meldrum DR. Antibiotics for vaginal oocyte aspiration. J In Vitro Fert Embryo Transf. 1989;6:1–2. doi: 10.1007/BF01134572. [DOI] [PubMed] [Google Scholar]
- 8.Kubota T, Ishi K, Takeuchi H. A study of tubo-ovarian and ovarian abscesses, with a focus on cases with endometrioma. J Obstet Gynaecol Res. 1997;23:421–426. doi: 10.1111/j.1447-0756.1997.tb00867.x. [DOI] [PubMed] [Google Scholar]