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Journal of Assisted Reproduction and Genetics logoLink to Journal of Assisted Reproduction and Genetics
. 2001 Feb;18(2):120–123. doi: 10.1023/A:1026543027300

CASE REPORT: Ovarian Hyperstimulation Syndrome Complicating a Spontaneous Singleton Pregnancy: A Case Report

Hee-Dong Chae 1, Eun-Joo Park 1, Sung-Hoon Kim 1, Chung-Hoon Kim 1, Byung-Moon Kang 1, Yoon Seok Chang 1
PMCID: PMC3455559  PMID: 11285979

Abstract

It has been known that most cases of ovarian hyperstimulation syndrome (OHSS) are associated with the use of exogenous gonadotropins to induce multiple ovulation. However, OHSS is infrequently associated with a spontaneous ovulatory cycle, usually in the case of multiple gestations, hypothyroidism, or polycystic ovarian syndrome. We report a case of severe OHSS in a spontaneously pregnant woman with no underlying disease.

Keywords: Ovarian hyperstimulation syndrome, normal spontaneous pregnancy

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REFERENCES

  • 1.Borenstein R, Elhalah U, Lunenfeld B, Schwartz ZS. Severe ovarian hyperstimulation syndrome: A reevaluated therapeutic approach. Fertil Steril. 1989;51(5):791–795. doi: 10.1016/s0015-0282(16)60668-4. [DOI] [PubMed] [Google Scholar]
  • 2.Rosen GF, Lew MW. Severe ovarian hyperstimulation in a spontaneous singleton pregnancy. Am J Obstet Gynecol. 1991;165(5pt1):1312–1313. doi: 10.1016/0002-9378(91)90357-w. [DOI] [PubMed] [Google Scholar]
  • 3.Zalel Y, Katz Z, Caspi B, Ben-Hur H, Dgani R, Insler V. Spontaneous ovarian hyperstimulation syndrome concomitant with spontaneous pregnancy in a woman with polycystic ovary disease. Am J Obstet Gynecol. 1992;167(1):122–124. doi: 10.1016/s0002-9378(11)91642-1. [DOI] [PubMed] [Google Scholar]
  • 4.Olatunbosun OA, Gilliland B, Brydon LA, Chizen DR, Pierson RA. Spontaneous ovarian hyperstimulation syndrome in four consecutive pregnancies. Clin Exp Obstet Gynecol. 1996;23(3):127–132. [PubMed] [Google Scholar]
  • 5.Schnorr JA, Jr, Miller H, Davis JR, Hatch K, Seeds J. Hyperreactio luteinalis associated with pregnancy: A case report and review of the literature. Am J Perinatol. 1996;13(2):95–97. doi: 10.1055/s-2007-994300. [DOI] [PubMed] [Google Scholar]
  • 6.Schenker JG, Polishuk WZ. The role of prostaglandins in ovarian hyperstimulation syndrome. Eur J Obstet Gynecol Reprod Biol. 1976;6(2):47–52. doi: 10.1016/0028-2243(76)90001-0. [DOI] [PubMed] [Google Scholar]
  • 7.Pride SM, Yuen BH, Moon SY. Clinical, endocrinologic, and intraovarian prostaglandin F response to H1 receptor blockade in the ovarian hyperstimulation syndrome: Studies in the rabbit model. Am J Obstet Gynecol. 1984;148(5):670–674. doi: 10.1016/0002-9378(84)90771-3. [DOI] [PubMed] [Google Scholar]
  • 8.Dourron NE, Williams DB. Prevention and treatment of ovarian hyperstimulation syndrome. Semin Reprod Endocrinol. 1996;14(4):355–365. doi: 10.1055/s-2008-1067980. [DOI] [PubMed] [Google Scholar]
  • 9.Clement PB. Tumor-like lesions of the ovary associated with pregnancy. Int J Gynecol Pathol. 1993;12(2):108–115. doi: 10.1097/00004347-199304000-00004. [DOI] [PubMed] [Google Scholar]
  • 10.Wajda KJ, Lucas JG, Marsh WL., Jr Hyperreactio luteinalis. Arch Pathol Lab Med. 1989;113(8):921–925. [PubMed] [Google Scholar]
  • 11.Lambers DS, Rosenn B. Hyperreactio luteinalis complicating a normal singleton pregnancy. Am J Perinatol. 1996;13(8):491–494. doi: 10.1055/s-2007-994434. [DOI] [PubMed] [Google Scholar]
  • 12.Golan A, Ron-El R, Herman A, Soffer Y, Weinraub Z, Caspi E. Ovarian hyperstimulation: An update review. Obstet Gynecol Surv. 1989;44(6):430–440. doi: 10.1097/00006254-198906000-00004. [DOI] [PubMed] [Google Scholar]

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