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Journal of Assisted Reproduction and Genetics logoLink to Journal of Assisted Reproduction and Genetics
. 1999 Aug;16(7):394–397. doi: 10.1023/A:1020554216254

Interleukin-1β Production by Human Preimplantation Embryos

Raoul Orvieto 1, Itai Bar-Hava, Ariela Schwartz, Michael Shelef, Jacob Ashkenazi, Jacob Bar, Zion Ben-Rafael
PMCID: PMC3455774  PMID: 10459525

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REFERENCES

  • 1.Ben-Rafael Z, Orvieto R. Cytokines-involvement in reproduction. Fertil Steril. 1992;58:1093–1099. doi: 10.1016/s0015-0282(16)55548-4. [DOI] [PubMed] [Google Scholar]
  • 2.Ben-Rafael Z, Orvieto R. Cytokines, in the early embryonic development, implantation and IVF. Genesis. 1995;13:25–29. [Google Scholar]
  • 3.Zolti M, Ben Rafael Z, Meirom R, Shemesh M, Bider D, Mashiach S, Apte RN. Cytokine involvement in oocytes and early embryos. Fertil Steril. 1991;56:265–272. doi: 10.1016/s0015-0282(16)54483-5. [DOI] [PubMed] [Google Scholar]
  • 4.Witkin SS, Liu HC, Davies OK, Rosenwaks Z. Tumor necrosis factor is present in maternal sera and embryo culture fluid during in vitro fertilization. J Reprod Immunol. 1991;19:85–93. doi: 10.1016/0165-0378(91)90008-e. [DOI] [PubMed] [Google Scholar]
  • 5.Austgulen R, Arntzen KJ, Vatten LJ, Kahn J, Sunde A. Detection of cytokines (interleukin-1, interleukin-6, transforming growth factor-β) and soluble tumor necrosis factor receptors in embryo culture fluids during in vitro fertilization. Hum Reprod. 1995;10:171–176. doi: 10.1093/humrep/10.1.171. [DOI] [PubMed] [Google Scholar]
  • 6.Simon C, Pellicer A, Polan ML. Interleukin-1 system cross-talk between embryo and endometrium in implantation. Hum Reprod. 1995;10:43–54. doi: 10.1093/humrep/10.suppl_2.43. [DOI] [PubMed] [Google Scholar]
  • 7.Baranao RI, Piazza LS, Rumi LS, Polak de Freid E. Determination of IL-1 and IL-6 levels in human embryo culture-conditioned media. Am J Reprod Immunol. 1997;37:191–194. doi: 10.1111/j.1600-0897.1997.tb00212.x. [DOI] [PubMed] [Google Scholar]
  • 8.Orvieto R, Bar-Hava I, Schwartz A, Shelef M, Ben-Rafael Z. Interleukin-2 production by human pre-implantation embryos. Gynecol Endocrinol. 1997;11:331–334. doi: 10.3109/09513599709152557. [DOI] [PubMed] [Google Scholar]
  • 9.De los Santos MJ, Mercader A, Frances A, Portoles E, Remohi J, Pellicer A, Simon C. Immunoreactive human embryonic interleukin-1 system and endometrial factors regulating their secretion during embryonic development. Biol Reprod. 1996;54:563–574. doi: 10.1095/biolreprod54.3.563. [DOI] [PubMed] [Google Scholar]
  • 10.Spandorfer SD, Barmat LI, Neuer A, Liu HC, Veeck L, Witkin SS, Rosenwaks Z: Interleukin-1β levels in the supernatant of conditioned media of embryos grown in autologous endometrial coculture are correlated with embryonic development and outcome for patients with a history of multiple implantation failure. Presented at the 54th Annual Meeting of the American Society for Reproductive Medicine, San Francisco, October 1998
  • 11.Mizuno D, Sorna GI. Endogenous and exogenous TNF therapy (EET therapy): Conceptual and experimental grounds. Ann Inst Pasteur Immunol. 1988;139:282–285. [PubMed] [Google Scholar]

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