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Journal of Urban Health : Bulletin of the New York Academy of Medicine logoLink to Journal of Urban Health : Bulletin of the New York Academy of Medicine
. 1998 Dec;75(4):896–902. doi: 10.1007/BF02344518

The pharmacoeconomic impact of antimicrobial therapy for peptic ulcer disease in a large urban jail

Jonathan Shuter 1,2,, David D Fletcher 1, Vito J Simone 1, Eran Y Bellin 1,2,4
PMCID: PMC3456001  PMID: 9854250

Abstract

Purpose

To determine the pharmacoeconomic impact of antimicrobial treatment of peptic ulcer disease (PUD) in a large urban jail.

Patients and Methods

Retrospective comparison of PUD-related pharmacy and laboratory expenditures over a 2-year period before and after the institution of a PUD treatment protocol with the priority ofHelicobacter pylori eradication for inmates in Rikers Island Correctional Facility.

Results

After the protocol was adopted, total pharmacy-related and laboratory-related expenses for PUD care decreased by 40.2%, and expenditures for ranitidine declined by 52.2%. There was an increase in spending for antimicrobial agents andH. pylori antibody testing, but this was insignificant compared to the savings generated by decreased ranitidine usage. Annual savings in our facility as a result of this intervention were $123,449.

Conclusions

Modern therapeutic strategies for PUD aimed at eradicatingH. pylori can result in significant savings in the institutional setting; these savings are largely attributable to the decreased usage of histamine-2 receptor antagonists.

Key Words: Cost, Jail, Peptic ulcer disease, Treatment

Full Text

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Footnotes

Montefiore-Rikers Island Health Services is a component of the Correctional Health Services of the New York City Department of Health and the New York City Health and Hospitals Corporation.

This work was presented in part at the 36th Interscience Conference on Antimicrobial Agents and Chemotherapy, New Orleans, Louisiana, September 15–18, 1996.

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