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. 1984 Jul;81(14):4465–4469. doi: 10.1073/pnas.81.14.4465

cis-acting mutations that affect rop protein control of plasmid copy number.

D R Moser, D Ma, C D Moser, J L Campbell
PMCID: PMC345611  PMID: 6205397

Abstract

A number of pMB1 derivatives provide a trans-acting function that can suppress lethal runaway replication of a temperature-sensitive copy-number mutant of NTP1. Deletion analysis indicates that the region of the pMB1 genome that contains the rop gene is required for this suppression. Mutant derivatives of the temperature-sensitive copy-number mutant plasmid whose conditional lethal phenotype is not suppressed in trans by the region encoding the rop gene have been isolated. These rop-insensitive derivatives contain single nucleotide changes within the RNA I coding region.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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