Abstract
A compact THz Free Electron Laser (FEL) isbeing used to perform irradiation ofbiological samples to investigate possiblegenotoxic effects. In order to evaluate theexact radiation dose absorbed by the singlecomponents of the samples it is necessaryto study the optical properties of thesamples, separating the contributions tothe radiation attenuation coefficientcoming from absorption and from diffusion.Spectroscopic measurements have beenperformed on different biological samples, comparing the experimental results withtheoretical models.
Keywords: Biological effects, blood, Free Electron Laser, lymphocytes, THz radiation
Full Text
The Full Text of this article is available as a PDF (291.4 KB).
References
- 1.Fenech, M.: The Cytokinesis-Block Micronucleus Technique: A Detailed Description of the Method and its Application to Genotoxicity Studies in Human Population,Mutation Res.285 (1993), 35-44. [DOI] [PubMed]
- 2.Gallerano, G.P, Doria, A., Giovenale, E. and Renieri, A.: Compact Free Electron Lasers: From Cherenkov to Waveguide Free Electron Lasers,Infrared Phys. and Tech.40 (1999), 161-174.
- 3.Ciocci, F., Bartolini, R., Doria, A., Gallerano, G.P., Giovenale, E., Kimmitt, M.F., Messina, G. and Renieri, A.: Operation of a Compact Free-Electron Laser in the Millimeter-Wave Region with a Bunched Electron Beam,Phys. Rev. Lett.70 (1993), 928-931. [DOI] [PubMed]
- 4.Ciocci, F., Doria, A., Gallerano, G.P., Giabbai, I., Kimmitt, M.F., Messina, G. and Renieri, A.: Observation of Coherent Millimeter and Submillimeter Emission from a Microtron-Driven Cherenkov Free-Electron Laser,Phys. Rev. Lett.66 (1991), 699-702. [DOI] [PubMed]
- 5.Doucas, G., Kimmitt, M.F., Doria, A., Gallerano, G.P., Giovenale, E., Messina, G., Andrews, H.L. and Brownell, J.H.: Determination of Longitudinal Bunch Shape by Means of Coherent Smith.Purcell Radiation,Phys. Rev. STAB5 (2002), 072802.1-072802.8.
- 6.Van De Hulst, H.C.:Light Scattering by Small Particles, Dover, 1981.
- 7.Cole, K.S. and Cole, R.H.: Dispersion and Absorption in Dielectrics: I. Alternating Current Characteristics,J. Chem. Phys.9 (1941), 341-351.
- 8.Gabriel, C., Gabriel, S. and Corthout, E.: The Dielectric Properties of Biological Tissues: III. Parametric Models for the Dielectric Spectrum of Tissues,Phys. Med. Biol.41 (1996), 2271-2293. [DOI] [PubMed]
- 9.Born M., Wolf E. Principles of Optics. Oxford: Pergamon Press; 1975. [Google Scholar]