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. Author manuscript; available in PMC: 2013 Sep 24.
Published in final edited form as: Small. 2012 Jul 6;8(18):2819–2822. doi: 10.1002/smll.201200333

Figure 3.

Figure 3

Tumor-associated macrophages (TAMs) treated with macrolide-gold nanorods (AuNRs) induce cell death in co-cultured breast adenocarcinoma cells. Macrolide-AuNR-loaded TAM nuclei were labeled with 4′,6-diamidino-2-phenylindole (DAPI, blue) and seeded onto MCF7 breast cell cultures at 50% plating densities. Confocal fluorescence microscopy using the apoptotic/necrotic nuclear marker, ethidium homodimer-1 (EthD-1, red), shows cytotoxicity exclusive to breast adenocarcinoma cells. Scale bar represents 50μm.