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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1982 Jun;79(12):3707–3710. doi: 10.1073/pnas.79.12.3707

Nickel-containing factor F430: chromophore of the methylreductase of Methanobacterium.

W L Ellefson, W B Whitman, R S Wolfe
PMCID: PMC346495  PMID: 6954513

Abstract

The yellow chromophore of the methyl-coenzyme M methylreductase of Methanobacterium thermoautotrophicum has been found to be the nickel-containing factor F430. Treatment of 63Ni-labeled methylreductase with 80% aqueous methanol released the radiolabel as well as the yellow chromophore; both properties were associated with a single compound that was found to be identical to F430, the stoichiometry being 1 mol of nickel per mol of F430 and 2 mol of F430 per mol of methylreductase.

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Selected References

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