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The Journal of Pediatric Pharmacology and Therapeutics : JPPT logoLink to The Journal of Pediatric Pharmacology and Therapeutics : JPPT
. 2005 Oct-Dec;10(4):248–253. doi: 10.5863/1551-6776-10.4.248

Oxcarbazepine: A Brief Review

Stephanie J Phelps 1,2,4,, James W Wheless 2,3,4
PMCID: PMC3468076  PMID: 23118640

Abstract

Oxcarbazepine is a new anticonvulsant with an active metabolite. It is approved as mono- or adjunctive therapy for partial seizures in adults and children older than 4 years of age and as adjunctive therapy in children 2 years and older. Its spectrum of anticonvulsant activity is comparable to carbamazepine, but it has an improved pharmacokinetic profile, is better tolerated and is associated with few clinically significant drug-drug interactions.

Keywords: anticonvulsant, carbamazepine, oxcarbazepine

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