Abstract
Purpose: To determine if a soft insemination catheter increases pregnancy rates.
Methods: Seven hundred forty-seven consecutive intrauterine insemination (IUI) cycles in 364 women in a reproductive endocrinology office between October 1998 and March 2000. Patients with even birth years were inseminated with the Tomcat catheter, and those with odd birth year with the Wallace IUI catheter. Clinical pregnancy rates were compared.
Results: The Wallace catheter group included 180 women for 372 cycles and an overall pregnancy rate of 16.4%. The Tomcat catheter group included 184 women for 375 cycles and an overall pregnancy rate of 18.1%. This difference is not statistically significant (P = 0.61). Potential confounders were accounted for.
Conclusions: When comparing the softer Wallace catheter to the less pliable Tomcat catheter during IUI cycles, there was no significant difference in pregnancy rate when using a standard gentle technique that includes not touching the top of the fundus with the catheter.
Keywords: Intrauterine insemination (IUI), catheter, Wallace, Tomcat, endometrium
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REFERENCES
- 1.Lavie O, Margolioth EJ, et al. Ultrasonographic endometrial changes after intrauterine insemination: A comparison of two catheters. Fertil Steril. 1997;68:731–734. doi: 10.1016/s0015-0282(97)00281-1. [DOI] [PubMed] [Google Scholar]
- 2.Goudas VT, Hammitt DG, Damario MA, Session DR, Singh AP, Dumesic DA. Blood on the embryo transfer catheter is associated with decreased rates of embryo implantation and clinical pregnancy with the use of in vitro fertilization-embryo transfer. Fertil Steril. 1998;70:878–882. doi: 10.1016/s0015-0282(98)00315-x. [DOI] [PubMed] [Google Scholar]
- 3.Wood EG, Batzer FR, Go KJ, Gutmann JN, Corson SL. Ultrasound-guided soft catheter embryo transfers will improve pregnancy rates in in vitro fertilization. Hum Reprod. 2000;15:107–112. doi: 10.1093/humrep/15.1.107. [DOI] [PubMed] [Google Scholar]
- 4.Wolcott R, Stranger J. Potentially important variables identi-fied by transvaginal ultrasound-guided embryo transfer. Hum Reprod. 1997;12(5):963–966. doi: 10.1093/humrep/12.5.963. [DOI] [PubMed] [Google Scholar]
- 5.Egbase PE, al-Sharhan M, al-Othman S, al-Mutawa M, Udo EE, Grudzinskas JG. Incidence of microbial growth from the tip of the embryo transfer catheter after embryo transfer in relation to clinical pregnancy rate following in-vitro fertilization and embryo transfer. Hum Reprod. 1996;11(8):1687–1689. doi: 10.1093/oxfordjournals.humrep.a019470. [DOI] [PubMed] [Google Scholar]
- 6.Van Voorhis BJ, Barnett M, Sparks AET, Syropp CH, Rosenthal G, Dawson J. Effect of total motile sperm count on the efficacy and cost-effectiveness of intrauterine insemination and in vitro fertilization. Fertil Steril. 2001;75:661–668. doi: 10.1016/s0015-0282(00)01783-0. [DOI] [PubMed] [Google Scholar]
- 7.Dickey RP, Pyrzak R, Lu PY, Taylor SN, Rye PH. Comparison of sperm quality necessary for successful intrauterine insemination with World Health Organization threshold values for normal sperm. Fertil Steril. 1998;71:684–689. doi: 10.1016/s0015-0282(98)00519-6. [DOI] [PubMed] [Google Scholar]
- 8.Montanaro Gauci M, Kruger TF, Coetzee K, Smith K, Van Der Merwe JP, Lombard CJ. Stepwise regression analysis to study male and female factors impacting on pregnancy rate in an intrauterine insemination programme. Andrologia. 2000;33:135–141. doi: 10.1046/j.1439-0272.2001.00428.x. [DOI] [PubMed] [Google Scholar]
- 9.Goverde AJ, McDonnell J, Vermeiden JPW, Schats R, Rutten FFH, Shoemaker Intrauterine insemination or in-vitro fertilization in idiopathic subfertility and male subfertility: A randomized trial and cost effectiveness analysis. Lancet. 2000;355:13–18. doi: 10.1016/S0140-6736(99)04002-7. [DOI] [PubMed] [Google Scholar]
- 10.Hearns-Stokes RM, Miller BT, et al. Pregnancy rates after embryo transfer depend on the provider at embryo transfer. Fertil Steril. 2000;74(1):80–86. doi: 10.1016/s0015-0282(00)00582-3. [DOI] [PubMed] [Google Scholar]