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. 1982 Sep;79(17):5327–5331. doi: 10.1073/pnas.79.17.5327

Dependence of locally measured cellular deformability on position on the cell, temperature, and cytochalasin B.

N O Petersen, W B McConnaughey, E L Elson
PMCID: PMC346889  PMID: 6957866

Abstract

We describe an approach to exploring cell surface-cytoskeleton interactions through direct measurements of the mechanical resistance of living cells to locally applied forces. These measurements are sensitive to variations in structure across the cell and at various depths below its surface. We find that local cellular deformability depends on the temperature and on the integrity of the cytoskeleton. Cytochalasin B increases the deformability of all regions of the cell except the nucleus.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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