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. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Hypertension. 2012 Oct 8;60(5):1273–1279. doi: 10.1161/HYPERTENSIONAHA.112.196295

Table 3.

Baseline Cardiovascular Parameters, Blood Pressure Response to Ganglionic Blockade and Statistical descriptors of individual frequency distribution curves from HdbHPTP1B, HdbKPTP1B, KdbHPTP1B and KdbKPTP1B mice.

Lean Obese
Parameter HdbHPTP1B HdbKPTP1B KdbHPTP1B KdbKPTP1B
    MAP (mmHg) 114 ± 2 108 ± 4 127 ± 2* 115 ± 2†
    DBP 105 ± 3 100 ± 4 114 ± 2* 103 ± 3†
    SBP 124 ± 3 119 ± 4 133 ± 3* 125 ± 3
    HR 522 ± 15 551 ± 16 488 ± 9 492 ± 18
Response to Ganglionic Blockade
    Δ MAP (%) -26 ± 3 -31 ± 2 -39 ± 4* -35 ± 4*
Statistical Descriptors of Frequency Distribution Curves (Figure 2)
    SKEW -0.06 ± 0.15 -0.79 ± 0.44 -0.22 ± 0.35 0.17 ± 0.05
    STD of MAP 14.6 ± 0.8 13.1 ± 3.5 21.4 ± 2.2* 14.1 ± 1.7†
    Frequency over 140 mmHg (%) 7 ± 3 4 ± 2 28 ± 5* 4 ± 2†
*

p<0.05 vs. HdbHPTP1B

†

p<0.05 vs. KdbHPTP1B.