Table 5. Cox Regression Model of Hazard Ratio for IOP<5mmHg, sustained for at least 30 days.
| Univariate n=6,785 events=126 |
Multivariate n=6,540 event=97 |
||||||
|---|---|---|---|---|---|---|---|
| Events/ At Risk |
Hazard Ratio (95% Confidence Interval) |
p- value |
Events/ At Risk |
Hazard Ratio (95% Confidence Interval) |
p- value |
||
| Age | <18 | 45/973 | 4.97 (2.58 - 9.57) | <.001 | 36/933 | 2.92 (1.20 - 7.10) | 0.15 |
| 18-25 | 22/897 | 2.50 (1.21 - 5.15) | 19/878 | 2.27 (0.98 - 5.27) | |||
| 26-35 | 15/1483 | Reference | 12/1458 | Reference | |||
| 36-45 | 15/1300 | 1.19 (0.53 - 2.65) | 11/1275 | 0.99 (0.40 - 2.43) | |||
| 46-55 | 13/983 | 1.39 (0.63 - 3.08) | 9/963 | 1.00 (0.35 - 2.85) | |||
| 56-65 | 6/556 | 1.14 (0.39 - 3.35) | 5/548 | 0.79 (0.22 - 2.82) | |||
| >65 | 7/497 | 1.87 (0.69 - 5.07) | 5/485 | 0.84 (0.24 - 2.97) | |||
| Race | White | 73/4755 | Reference | 0.002 | 55/4629 | Reference | 0.74 |
| African-derived | 42/1208 | 2.22 (1.42 - 3.46) | 32/1148 | 1.25 (0.71 - 2.22) | |||
| Other | 11/822 | 1.10 (0.52 - 2.30) | 10/763 | 1.03 (0.49 - 2.14) | |||
| Contralateral uveitis | No | 8/1170 | Reference | 0.02 | 8/1144 | Reference | 0.41 |
| Yes | 118/5615 | 2.35 (1.14 - 4.87) | 89/5396 | 1.39 (0.63 - 3.07) | |||
| Hypertension | No | 86/5547 | Reference | 0.006 | 70/5351 | Reference | 0.052 |
| Yes | 40/1238 | 1.89 (1.20 - 2.97) | 27/1189 | 2.04 (0.99 - 4.20) | |||
| Systemic Diseases | Behçet’s disease, HLA-B27, spondyloarthropathy, and/or Sarcoidosis |
57/1846 | 1.80 (1.20 - 2.72) | 0.005 | 43/1775 | 0.79 (0.42 - 1.49) | 0.46 |
| Juvenile idiopathic arthritis |
33/329 | 6.13 (3.83 - 9.81) | <.001 | 25/297 | 2.04 (0.79 - 5.31) | 0.14 | |
| Type of Uveitis | Anterior Uveitis | 74/3609 | Reference | <.001 | 61/3459 | Reference | <.001 |
| Intermediate Uveitis | 6/1197 | 0.20 (0.07 - 0.58) | 4/1169 | 0.17 (0.05 - 0.56) | |||
| Posterior Uveitis | 3/1112 | 0.10 (0.03 - 0.31) | 2/1087 | 0.11 (0.03 - 0.45) | |||
| Panuveitis | 43/867 | 1.93 (1.24 - 3.01) | 30/825 | 1.25 (0.67 - 2.35) | |||
| Duration of uveitis at presentation |
<6 months | 18/2749 | Reference | <.001 | 10/2613 | Reference | 0.002 |
| 6 months to 2 years | 15/1401 | 1.46 (0.67 - 3.17) | 14/1382 | 1.52 (0.59 - 3.94) | |||
| 2 to 5 years | 27/1134 | 3.36 (1.68 - 6.69) | 26/1112 | 4.53 (1.94 - 10.61) | |||
| Greater than 5 years | 66/1501 | 6.13 (3.33 - 11.26) | 47/1433 | 3.08 (1.30 - 7.31) | |||
| Prior Cataract Surgery by Type |
None | 32/* | Reference | <.001 | 19/* | Reference | <.001 |
| Phacoemulsification | 13/* | 4.21 (2.15 - 8.27) | 13/* | 4.87 (2.25 - 10.55) | |||
| Extracapsular cataract extraction (ECCE) |
17/* | 8.00 (4.34 - 14.73) | 16/* | 6.50 (3.14 - 13.45) | |||
| Intracapsular cataract extraction (ICCE) |
11/* | 22.20 (9.32 - 52.89) | 8/* | 12.19 (3.78 - 39.30) | |||
| Pars plana lensectomy | 19/* | 25.63 (13.86 - 47.40) |
18/* | 8.51 (3.12 - 23.21) | |||
| Unknown | 34/* | 13.98 (8.10 - 24.13) | 23/* | 7.28 (3.31 - 16.00) | |||
| Prior Pars Plana Vitrectomy |
No | 89/* | Reference | <.001 | 63/* | Reference | 0.008 |
| Yes | 37/* | 5.58 (3.61 - 8.62) | 34/* | 2.03 (1.21 - 3.42) | |||
| Prior Retinal Detachment Surgery |
No | 118/* | Reference | <.001 | 91/* | Reference | 0.88 |
| Yes | 8/* | 4.87 (2.24 - 10.59) | 6/* | 0.92 (0.29 - 2.89) | |||
| Anterior chamber cells | Quiet | 72/* | Reference | 0.03 | 58/* | Reference | 0.45 |
| 0.5+ | 26/* | 1.94 (1.20 - 3.14) | 19/* | 0.86 (0.46 - 1.58) | |||
| 1+ | 14/* | 1.76 (0.93 - 3.35) | 13/* | 1.24 (0.63 - 2.46) | |||
| 2+ | 4/* | 0.78 (0.28 - 2.14) | 3/* | 0.31 (0.08 - 1.14) | |||
| 3+ or worse | 5/* | 1.87 (0.76 - 4.63) | 4/* | 0.97 (0.32 - 2.94) | |||
| Structural complications | Exudative detachment | 9/* | 14.15 (6.77 - 29.55) | <.001 | 9/* | 5.25 (1.86 - 14.80) | 0.002 |
*
The number at risk for time-varying characteristics changes over followup, and is therefore not reported as a number of patients