Spontaneous splenic infarction associated with sumatriptan use

Abstract

Triptans are specific agonists of the serotonergic 5-HT_1B/1D receptors that have increasingly been used in the treatment of migraine and cluster headaches. Though they are generally considered safe, there have been a few reports of myocardial infarction and stroke associated with triptan use. We report a patient who developed spontaneous splenic infarction after the use of sumatriptan for the treatment of migraine headache.

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